Yu-shan Huang

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BACKGROUND The objective of this study was to investigate myocardial deformation of the left atrium (LA) assessed by two-dimensional speckle tracking echocardiography in patients with permanent atrial fibrillation (AF) and its value for risk stratification for stroke. METHODS We recruited 66 consecutive patients with permanent AF who were referred to our(More)
Nasopharyngeal carcinoma (NPC), one of the most common cancers in Southeast Asia, is commonly diagnosed late due to its deep location and vague symptoms. To identify biomarkers for improving NPC diagnosis, we established a proteomic platform for detecting aberrant serum proteins in nude mice bearing NPC xenografts. We first removed the three most abundant(More)
The first confirmed case of H7N9 infection outside mainland China has been documented in Taiwan. We followed the close contacts with this confirmed cases by serological determination for hemagglutinin inhibition (HI) activity, to assess the potential of human-to-human transmission of H7N9 virus. The HI assay was performed by a standard procedure according(More)
During murine embryogenesis, primitive erythroblasts enter the circulation as immature nucleated cells and progressively mature as a semisynchronous cohort, enucleating between E12.5 and E16.5. In this report, we examine the mechanical properties of these cells to determine how their mechanical development differs from that of definitive erythroid cells,(More)
OBJECTIVE To investigate the aberrant DNA methylation in promoter region of estrogen receptor alpha (ERalpha) in atherosclerosis (As) and the possible involvement of homocysteine (Hcy) in its pathogenesis. METHODS The blood samples were collected from 54 patients with As approved by carotid colorized ultrasound examination and 28 healthy control subjects.(More)
BACKGROUND Natural killer (NK) cells are important effector cells in the defense against tumors. The present study retrospectively examines the intratumoral NK cells in primary resected esophageal squamous cell carcinoma (ESCC) and the correlation between the patient' outcome and the intratumoral NK cells infiltration. METHODS Immunohistochemistry was(More)
BACKGROUND Although the mortality rates have decreased over the past few decades, neonatal meningitis is still a severe disease with high morbidity. Moreover, approximately 40% of survivors exhibit neurological sequelae. Escherichia coli is the major Gram-negative bacterial pathogen in neonatal meningitis. The N-terminal β-barrel domain of the outer(More)
UNLABELLED Numerous studies have investigated the association between xeroderma pigmentosum complementation group C (XPC) poly (AT) deletion/insertion (PAT -/+) polymorphism and cancer susceptibility; however, the findings are inconsistent. Therefore, we performed a meta-analysis based on 32 publications including 10,214 cases and 11,302 controls to acquire(More)
The cancer cell secretome may contain potentially useful biomarkers. Previously, we have analyzed the colorectal carcinoma (CRC) cell secretome. In this study, tumor-associated antigen 90K (TAA90K)/Mac-2 binding protein (Mac-2BP), one of the CRC cell secreted proteins, was chosen for evaluation as a potential CRC biomarker because its mRNA level was also(More)
Black porgy, Acanthopagrus schlegeli Bleeker, is a marine protandrous hermaphrodite fish. All are functional males at 1-2 yr of age and then become either males or females at 3 yr of age. To study the process of sex change in this species, mRNA transcripts of two estrogen receptors (ERalpha and ERbeta) and an androgen receptor (AR) were monitored. An AR(More)