Yu-kwan Tong

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BACKGROUND The detection of circulating nucleic acids has long been explored for the non-invasive diagnosis of a variety of clinical conditions. In earlier studies, detection of circulating DNA has been investigated for the detection of various forms of cancer. Metastasis and recurrence in certain cancer types have been associated with the presence of high(More)
Severe acute respiratory syndrome (SARS) is a global health concern. In Hong Kong, two major outbreaks, one hospital based and the other in the Amoy Gardens apartments, were identified. The frequency of diarrhoea, admission to intensive care, and mortality differed significantly between the two outbreaks. We did genomic sequencing for viral isolates from(More)
kill, or sell food animals, and persons who prepare and serve food. (More than one third of the cases in China with onset of SARS before February 1, 2003, were in food handlers [3].); 2) public transportation workers and airline crew (4); and 3) laboratory workers handling samples or items contaminated with SARS-associated coronavirus (5). In Singapore, 2(More)
An outbreak of severe acute respiratory syndrome (SARS) has affected 33 countries on five continents, with 8098 suspected and probable cases and 774 deaths. During the SARS epidemic, more than 1700 infected cases have been reported in Hong Kong. The disease is infectious, particularly within the healthcare setting. Early diagnosis is essential to control(More)
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