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  • Weidong Li, Yu Zhou, +11 authors Tyrone D. Cannon
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2007 (First Publication: 13 November 2007)
  • Disrupted-in-schizophrenia 1 (DISC1) was initially discovered through a balanced translocation (1;11)(q42.1;q14.3) that results in loss of the C terminus of the DISC1 protein, a region that isContinue Reading
  • Tanggang Deng, Guobei Yan, +15 authors Mao Ye
  • Medicine, Chemistry
  • Proceedings of the National Academy of Sciences
  • 2018 (First Publication: 16 April 2018)
  • Significance Previous studies have demonstrated that p21 occupies a central position in cell-cycle regulation and DNA damage responses. As an unstable protein, the regulation of p21 stability hasContinue Reading
  • Yu Zhou, Bal Ram Singh
  • Chemistry, Medicine
  • Protein expression and purification
  • 2004 (First Publication: 1 March 2004)
  • Botulinum neurotoxins (BoNTs) are highly potent toxins that inhibit neurotransmitter release from peripheral cholinergic synapses and associate with infant botulism. BoNT is a approximately 150kDaContinue Reading