Yu Zhang

Sort by:

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates.

Cyril Boyault, Yu Zhang, +8 authors Saadi Khochbin
Genes & development
2007

A cellular defense mechanism counteracts the deleterious effects of misfolded protein accumulation by eliciting a stress response. The cytoplasmic deacetylase HDAC6 (histone deacetylase 6) was… (More)

The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer.

Y. B. Chen, Lin Shi, +8 authors Yongfeng Shang
The Journal of biological chemistry
2008

SOX genes encode a family of high-mobility group transcription factors that play critical roles in organogenesis. The functional specificity of different SOX proteins and the tissue specificity of a… (More)

Synergistic effects of interleukin-1β and interleukin-17A antibodies on collagen-induced arthritis mouse model.

Yu Zhang, Guiping Ren, +7 authors De-shan Li
International immunopharmacology
2013

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that mainly causes the synovial joint inflammation and cartilage destruction. Both interleukin-1β (IL-1β) and Interleukin-17… (More)

The histone modifications governing TFF1 transcription mediated by estrogen receptor.

Yanyan Li, Luyang Sun, +5 authors Yongfeng Shang
The Journal of biological chemistry
2011

Transcription regulation by histone modifications is a major contributing factor to the structural and functional diversity in biology. These modifications are encrypted as histone codes or histone… (More)

Pyk2 promotes tumor progression in multiple myeloma.

Yu Zhang, Michele Moschetta, +19 authors Irene M Ghobrial
Blood
2014

Proline-rich tyrosine kinase 2 (Pyk2) is a member of the focal adhesion kinase family that has been recently linked to tumor development. However, its role in modulating multiple myeloma (MM) biology… (More)

Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells.

Bin Shi, Jing Liang, +10 authors Yongfeng Shang
Molecular and cellular biology
2007

Essential for embryonic development, the polycomb group protein enhancer of zeste homolog 2 (EZH2) is overexpressed in breast and prostate cancers and is implicated in the growth and aggression of… (More)

Very high fructose intake increases serum LDL-cholesterol and total cholesterol: a meta-analysis of controlled feeding trials.

Yu Zhang, Tao An, Rong Cheng Zhang, Qiong Zhou, Yan Huang, Jian Zhang
The Journal of nutrition
2013

Fructose is widely used as a sweetener in the production of many foods, yet the relation between fructose intake and cholesterol remains uncertain. In this study, we performed a systematic review and… (More)

FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells

Juan Du, Lin Li, +8 authors Jun Lu
Breast Cancer Research and Treatment
2011

Polycomb group (PcG) proteins have recently been shown related to cancer development. The PcG protein EZH2 is involved in progression of prostate and breast cancers, and has been identified as a… (More)

DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection.

Zhiquan Wang, J Liu, +8 authors J-D. Ding
Annals of neurology
2011

OBJECTIVE Loss of function mutations of Park7/DJ-1 gene increase the susceptibility of dopaminergic cells to reactive oxygen species and cause early onset familial Parkinson disease (PD). However,… (More)

Consistent and differential genetic aberrations between esophageal dysplasia and squamous cell carcinoma detected by array comparative genomic hybridization.

Zhi-Zhou Shi, Li Shang, +9 authors Ming-rong Wang
Clinical cancer research : an official journal of…
2013

PURPOSE Our aim was to identify frequent genomic aberrations in both esophageal squamous cell carcinoma (ESCC) and esophageal dysplasia and to discover important copy number-driving genes and… (More)

Filter Results:

Publication Year

Publication Type

Co-author

Journals and Conferences