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Cadmium (Cd) has been shown to bind to the human estrogen receptor (ER), yet studies on Cd's estrogenic effects have yielded inconsistent results. In this study, we investigated the effects of Cd on DNA synthesis and its simultaneous effects on both genomic (mediated by nuclear ER (nER)) and non-genomic (mediated by membrane-bound ER (mER)) signaling in(More)
This paper presents a novel image smoothing approach using a space-filling curve as the reduced domain to perform separation of edges and details. This structure-aware smoothing effect is achieved by modulating local extrema after empirical mode decomposition; it is highly effective and efficient since it is implemented on a one-dimensional curve instead of(More)
OBJECTIVE Maintenance treatment for clinically stable patients with schizophrenia is usually provided by Chinese primary care physicians, but no study has investigated smoking rates in this population. This study investigated the rate of smoking and its associations with sociodemographic and clinical characteristics and quality of life (QOL) in patients(More)
A practical image enhancing technique is presented as a preprocessing step for painterly rendering and image stylization, which transforms the input image mimicking the vision of artists. The new method contains mainly two parts dealing with artistic enhancement and color adjustment, respectively. First, through feature extraction and simplification, an(More)
Wireframe is a modeling tool widely used in industrial geometric design. The term wireframe refers to two sets of curves, with the property that each curve from one set intersects with each curve from the other set. Akin to the mu-, v-isocurves in a tensor-product surface, the two sets of curves in a wireframe span an underlying surface. In many industrial(More)
Image smoothing prefers a good metric to identify dominant structures from textures adaptive of intensity contrast. In this paper, we drop on a novel directional anisotropic structure measurement (DASM) toward adaptive image smoothing. With observations on psychological perception regarding anisotropy, non-periodicity and local directionality, DASM can well(More)
We propose a novel method that automatically analyzes stroke-related artistic styles of paintings. A set of adaptive interfaces are also developed to connect the style analysis with existing painterly rendering systems, so that the specific artistic style of a template painting can be effectively transferred to the input photo with minimal effort. Different(More)
An important surface modeling problem in CAD is to connect two disjoint B-spline patches with the second-order geometric continuity. In this paper we present a study to solve this problem based on the surface extension algorithm [Computer-Aided Design 2002; 34:415– 419]. Nice properties of this extension algorithm are exploited in depth and thus make our(More)