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We present a method to identify the dynamics of a human arm controlled by an implanted functional electrical stimulation neuroprosthesis. The method uses Gaussian process regression to predict shoulder and elbow torques given the shoulder and elbow joint positions and velocities and the electrical stimulation inputs to muscles. We compare the accuracy of(More)
We present a method for controlling a neuroprosthesis for a paralyzed human arm using functional electrical stimulation (FES) and characterize the errors of the controller. The subject has surgically implanted electrodes for stimulating muscles in her shoulder and arm. Using input/output data, a model mapping muscle stimulations to isometric endpoint forces(More)
We present a method for controlling a neuroprosthesis for a paralyzed human arm using functional electrical stimulation (FES). The subject has surgically implanted electrodes for stimulating muscles in her shoulder and arm. Using input/output data, a model is identified that describes the mapping from muscle stimulations to the endpoint force measured at(More)
A major challenge in controlling multiple-input multiple output functional electrical stimulation systems is the large amount of time required to identify a workable system model due to the high dimensionality of the space of inputs. To address this challenge we are exploring optimal methods to sample the input space. In this paper we present two methods(More)
BACKGROUND AND AIMS Measles infection causes immune suppression that contributes to morbidity and mortality of the patients; the mechanism is poorly understood. Regulatory T cells (Treg) play a critical role in immune suppression. Integrin alphavbeta6 (avb6) is associated with Treg's function. This study aims to investigate into the mechanism by which(More)
Functional electrical stimulation (FES) can be used to restore movement control following paralysis. For complex multijoint systems, it is becoming increasingly apparent that closed-loop controllers are needed. Designing a closed-loop control system is easiest when the open-loop system is stable. In this study we developed a computational model to assess(More)
We present a method to experimentally identify the inverse dynamics of a human arm. We drive a person's hand with a robot along smooth reaching trajectories while measuring the motion of the shoulder and elbow joints and the force required to move the hand. We fit a model that predicts the shoulder and elbow joint torques required to achieve a desired arm(More)
OBJECTIVE The present retrospective study aimed to analyze the optimal time to initiate enteral nutrition (EN) in patients with severe acute pancreatitis at a single Chinese institution (China Medical University Hospital). METHODS A total of 1196 patients with severe acute pancreatitis were admitted in the intensive care unit between November 2003 and(More)
In this paper we present a method to stimulate multiple muscles in a human arm to perform interaction tasks, using an implanted Functional Electrical Stimulation (FES) neuroprosthesis. The unstable effect arising from interaction tasks is considered, and the arm stability is directly treated as one of the control objectives in the controller design. By(More)
The airway epithelial barrier function is important in maintaining the homeostasis in the body. A number of airway disorders are associated with the epithelial barrier dysfunction. The present study aims to elucidate a possible mechanism by which the proteolytic allergens compromise the epithelial barrier function. The airway epithelial cell line, RPMI 2650(More)