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This paper presents a method for sharing and hiding secret images. The method is modiÿed from the (t; n) threshold scheme. (Comput.Graph. 26(5)(2002)765) The given secret image is shared and n shadow images are thus generated. Each shadow image is hidden in an ordinary image so as not to attract an attacker's attention. Any t of the n hidden shadows can be(More)
A pharmacophore model, Hypo1, was built on the basis of 21 training-set indole compounds with varying levels of antiproliferative activity. Hypo1 possessed important chemical features required for the inhibitors and demonstrated good predictive ability for biological activity, with high correlation coefficients of 0.96 and 0.89 for the training-set and(More)
The interaction of newly synthesised water-soluble planar complexes of general structure [Pt(diimine)(N,N-dihydroxyethyl-N'-benzoylthioureato)]+Cl- with DNA was investigated by means of DNA melting studies, CD spectroscopy, and DNA gel mobility studies. Addition of stoichometric amounts of [Pt(diimine)H2L-S,O]Cl complexes to polynucleotides caused a(More)
Hepatitis C virus (HCV) infection is a severe liver disease that often leads to liver cirrhosis and hepatocellular carcinoma (HCC). Current therapy is inadequate to conquer this viral disease. In this study, we identified parthenolide (1), an active component in feverfew, a popular remedy for fever and migraine, as a lead compound with an EC50 value of 2.21(More)
Spoofing attack (or copy attack) is a fatal threat for biometric authentication systems. In this paper, we present a novel liveness detection method based on frequency entropy of image sequences against the photograph spoofing. By splitting the color video of face region into RGB channels, we can obtain the time sequences of each color channel. Then, three(More)
Video-based face recognition has drawn a lot of attention in recent years. On the other hand, Bag-of-visual Words (BoWs) representation has been successfully applied in image retrieval and object recognition recently. In this paper, a video-based face recognition approach which uses visual words is proposed. In classic visual words, Scale Invariant Feature(More)
Video-based Heart Rate Measurement has drawn a lot of attention in recent years. A few papers have been proposed in this work and most of them applied Fourier transform peak interval determination method for heart rate measurement. However, the analyzing duration for one outcome in these methods is usually longer than 15 seconds. This is because that the(More)
Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based anticancer agent. For this purpose, 5,6-fused bicyclic heteroaromatic scaffolds were designed and synthesized through shuffling of the nitrogen from the N-1 position or by insertion of one or two nitrogen atoms into the indole(More)
BPR0L075 (2) is a potential anticancer drug candidate designed from Combretastatin A-4 (1) based on the bioisosterism principle. Metabolites of 2, proposed from in vitro human microsome studies, were synthesized, leading to the identification of metabolite-derived analogue 10 with 40-350 pM potency against various cancer cell lines. Insights gained from the(More)