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Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage‐dependent anion channel‐1
Peripheral benzodiazepine receptor (PBR) is a multifunctional protein mainly found on the outer mitochondrial membrane. PBR expression is increased by tumor necrosis factor‐α (TNF‐α) in endothelialExpand
Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker
Bladder cancer (BCa) is one of the most common urothelial cancers with still noticeable incidence rate. Early detection of BCa is highly correlated with successful therapeutic outcomes. We previouslyExpand
Anthocyanin-Rich Extract from Red Chinese Cabbage Alleviates Vascular Inflammation in Endothelial Cells and Apo E−/− Mice
  • H. Joo, S. Choi, +7 authors B. Jeon
  • Chemistry, Medicine
  • International journal of molecular sciences
  • 1 March 2018
Anthocyanins, the most prevalent flavonoids in red/purple fruits and vegetables, are known to improve immune responses and reduce chronic disease risks. In this study, the anti-inflammatoryExpand
Extracellularly secreted APE1/Ref-1 triggers apoptosis in triple-negative breast cancer cells via RAGE binding, which is mediated through acetylation
The present study evaluated the mechanism of apoptosis caused by post-translational modification, hyperacetylation in triple-negative breast cancer (TNBC) cells. We previously showed thatExpand
Histone deacetylases inhibitor trichostatin A modulates the extracellular release of APE1/Ref-1.
Apurinic/apyrimidinic endonuclease 1/Redox factor-1 (APE1/Ref-1) can be acetylated via post-translational modification. We investigated the effect of an inhibitor of histone deacetylases on theExpand
Secreted APE1/Ref-1 inhibits TNF-α-stimulated endothelial inflammation via thiol-disulfide exchange in TNF receptor
Apurinic apyrimidinic endonuclease 1/Redox factor-1 (APE1/Ref-1) is a multifunctional protein with redox activity and is proved to be secreted from stimulated cells. The aim of this study was toExpand
Elevation of the Serum Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 in Coronary Artery Disease
Background and Objectives Apurinic/apyrimidinic endonuclease 1/redox effector factor-1 (APE1/Ref-1) is a multifunctional protein involved in the DNA base excision repair pathway, inflammation,Expand
The hexane fraction of Naematoloma sublateritium extract suppresses the TNF-α-induced metastatic potential of MDA-MB-231 breast cancer cells through modulation of the JNK and p38 pathways.
Naematoloma sublateritium (Fr.) P. Karst is a basidiomycete that has been used as traditional medicine. N. sublateritium produces a triterpenoid antitumor compound, clavaric acid, but, in general,Expand
Antioxidant and anticancer activity of fractions of the ethanol extract of Naematoloma sublateritium
Naematolma sublateritium (Fr.) P. Karst (family: Strophariaceae) is known as a chestnut mushroom. Although N. sublateritium is currently a popular and edible fungus in the USA, Japan and Korea, itsExpand
Plasma APE1/Ref-1 Correlates with Atherosclerotic Inflammation in ApoE−/− Mice
Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is involved in DNA base repair and reducing activity. However, the role of APE1/Ref-1 in atherosclerosis is unclear. Herein, weExpand