Yu. O. Zubova

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We studied the endocrine function of the noradrenergic system in the developing brain. The data on the age-related dynamics of the noradrenaline concentration in plasma and in the hypothalamus and mesencephalon–rhombencephalon before and after the formation of the blood–brain barrier indirectly indicates the possibility of noradrenaline secretion from the(More)
123 Ontogenetic development and functioning of an organism are regulated by intracellular chemical sig naling; the signal molecules are secreted by the neu roendocrine system and function as morphogenetic or transcription factors affecting target cells and organs via specific receptors. Among the great variety of chemical signals controlling the development(More)
The purpose of the study was to identify the characteristics of apoptosis in the kidneys, ureters and bladder of fetuses and newborns in the modeling of chronic intrauterine hypoxia, acute postnatal hypoxia and mixed hypoxia. An experiment was conducted on WAG rats for modeling high altitude hypoxia. Experimental animals were divided into four groups: I -(More)
We tested the hypothesis that brain-derived chemical stimuli contribute to direct endocrine regulation of peripheral organs during ontogeny before blood-brain barrier closure. Dopamine and gonadotropin-releasing hormone present in high concentration in peripheral blood only before blood-brain barrier closure were chosen as the chemical stimuli. It was shown(More)
12 The present study continues a series of experiments performed to revise our hypothesis on the endocrine function of the developing brain, which is observed from the time of formation of neurons to the time of formation of interneuronal synaptic connections and the blood–brain barrier (BBB). During this period, the brain secretes signal molecules,(More)
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