Yu. O. Nikishina

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Using the method of high performance liquid chromatography with electrochemical detection, the age dynamics of the content of noradrenaline (NA) in the brain, adrenal gland, and the organ of Zuckerkandl in prenatal (18th and 21st days of embryogenesis) and early postnatal (3, 7, 15, and 30th days) periods of development was studied. The potential(More)
The goal of the present study was to verify our hypothesis of humoral interaction between the norepinephrine secreting organs in the perinatal period of ontogenesis that is aimed at the sustaining of physiologically active concentration of norepinephrine in blood. The objects of the study were the transitory organs, such as brain, organ of Zuckerkandl, and(More)
The level of gene expression and the protein content of tyrosine hydroxylase and dopamine β-hydroxylase were determined. In the perinatal period of rats, when noradrenaline functions as a morphogenetic factor, the level of gene expression of these enzymes increased and the content of protein products of these genes was almost unchanged, indicating the(More)
Gene expression and content of the key enzymes involved in the synthesis of noradrenaline—tyrosine hydroxylase and dopamine beta-hydroxylase—was evaluated in the organ of Zuckerkandl of rats in the critical period of morphogenesis. High levels of mRNA and protein of both enzymes in the perinatal period of development and their sharp decline on day 30 of(More)
The study is devoted to investigating the humoral interaction of the organs that are major sources of the morphogenetic factor noradrenaline in the general circulation system of rats in the neonatal period of development. The change in the synthesis of noradrenaline in the central and peripheral organs when its synthesis in the brains of neonatal rats is(More)
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