Yu. N. Korobova

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We have previously studied the ll~-hydroxylation of androst-4-ene-3,17-dione (I) by means of Rhizopus nigricans [2], as well as the transformation of I and androsta-l,4-diene3,17-dione (II) by means of a Beauveria sp. culture [i]. As a continuation of the research we investigated the possibility of the hydroxylation of I and II with Tie~hemella hyalospora(More)
This work was devoted to an investigation of the process of microbiological conversion of Reichstein's substance S with the aid of fungi from the genus Penieillium. A whole series of different species of this microorganism was examined: Pen. arenarium, Pen. canescens Sopp, Pen. corymbiferum, Pen. cyclopium Westl, Pen. insectivorum Sopp, Pen. italieum(More)
Due to the demand for steroid horomones, the problem of the search for a cheap and available raw material for their synthesis is most important. One such material is sitosterol (I) obtained from the wastes of the wood-processing industry. The condition for its use for the synthesis of hormones is the splitting of the side chain in the sterol molecule. This(More)
mixture of steroids (~35 mg) to each plate. The corresponding spots were collected and eluted with methanol; evaporation of the solvent gave the residue (90 mg). It was dissolved in a mixture of chloroform (0.9 ml) and methanol (0.22 ml); after addition of water (6.75 ml), the mixture was left overnight at 0~ being periodically agitated. Filtration gave(More)
We have already shown that I can be oxidized by cultures of mycobacteria in the presence of a degradation inhibitor of the steroid skeleton, 8-hydroxyquinoline [I]. In the present work, we studied cultures of Myc. mucos~ 3-AP and ~c. flav~ B2 that in the presence of 8-hydroxyquinoline form oxidation products: androsta-l,4-diene-3,17-dione (II) (the two(More)
[in Russian], Moscow (1969), pp. 58-63. 3. E. F. Panarin and M. V. Solovskii, Antibiotiki, No. 10, 882-885 (1971). 4. I. T. Strukov, Antibiotiki, No. ii, 963-976 (1963). 5. R. H. Depue, A. G. Moat, and A. Bondi, Arch. Biochem., 107, 374-381 (1964). 6. R. Labia, Biochimie, 56, 1025-1030 (1974). 7. J. L. Longridge and D. Timms. J. Chem. Soc. (B), No. 5,(More)
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