Yu-Mei Xue

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Oxidative stress is one of the most important pathological mechanisms in neurodegenerative diseases and ischemia. Recent studies have indicated that the sonic hedgehog (SHH) signaling pathway is involved in these diseases, but the underlying mechanisms remains elusive. Here we report that the SHH pathway was activated in primary cultured cortical neurons(More)
The L-type calcium channel (LCC) plays a regulatory role in various physical and pathological processes. In the vasculature, LCCs mediate agonist-induced vascular smooth muscle contraction. However, whether LCC-mediated vessel responses to certain vasoconstrictors vary among species remains unclear. The coronary arteries were dissected from the hearts of(More)
BACKGROUND Tumor necrosis factor-alpha (TNF-α) is a pleiotropic proinflammatory cytokine and contributes to many kinds of cardiovascular diseases via its receptors (TNFR1/TNFR2). We hypothesize that TNF-α plays a role in the pathogenesis of chronic atrial fibrillation (AF). METHODS Sixty-seven consecutive patients who were scheduled to have cardiac(More)
Pattern Sturmian words introduced by Kamae and Zamboni KZ1, KZ2] are an analogy of Sturmian words for the maximal pattern complexity instead of the block complexity. S o f a r , t wo kinds of recurrent pattern Sturmian words are known, namely, rotation words and Toeplitz words. But neither a structural characterization nor a reasonable classiication of the(More)
The maximal pattern complexity of one-dimensional words has been studied in several papers [T. Kamae, L. Zamboni, Sequence entropy and the maximal pattern complexity of infinite words, Ergodic Theory Dynam. We study the maximal pattern complexity p * (k) of two-dimensional words. A two-dimensional version of the notion of strong recurrence is introduced. It(More)
Let A be a finite subset of Z 2. We say A tiles Z 2 with the translation set C, if any integer z ∈ Z 2 can be represented as z1 + z2, z1 ∈ A, z2 ∈ C in a unique way. In this case we call A a Z 2-tile and write A ⊕ C = Z 2. A tile A is said to be a normal Z 2-tile if there exists a periodic set C such that A ⊕ C = Z 2. We characterize all normal Z 2-tiles(More)
OBJECTIVE The objective of the present study is to analyze the epidemiological profile of patients with abnormal valvular structure and function and highlight the etiological spectrum and management of valvular heart disease (VHD) in a single cardiovascular center of Southern China in five years. METHODS The retrospective study included 19,428 consecutive(More)
OBJECTIVES To investigate the relationship between serum uric acid (SUA) and left atrial spontaneous echo contrast (LA-SEC) in non-valvular atrial fibrillation (AF) patients. METHODS We retrospectively screened 1,476 consecutive hospitalized patients with AF who underwent transesophageal echocardiography prior to radiofrequency catheter ablation, left(More)