Yu-Lin Wang

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In this paper, an 8-channel closed-loop neural-prosthetic SoC is presented for real-time intracranial EEG (iEEG) acquisition, epileptic seizure detection, and adaptive feedback stimulation control. The SoC is composed of 8 energy-efficient analog front-end amplifiers (AFEAs), a 10b delta-modulated SAR ADC (DMSAR ADC), a configurable bio-signal processor(More)
Epilepsy is one of the most common neurological disorders. Around 1% of the world's population is affected, and nearly 25% of the patients cannot be treated by available therapies. Recently, seizure-triggered feedback electrical stimulation has been proved to effectively suppress pathological brain activities [1], but devices with accurate detection and(More)
—The development of many telemedicine systems focus on the utility of communication techniques. However, the comfort of long-term Electrocardiogram (ECG) monitoring in daily life is necessary and is also an important unresolved issue. A wearable mobile electrocardiogram monitoring system (WMEMS) is proposed to monitor ECG in this study. It mainly consists(More)
OBJECTIVE Around 1% of the world's population is affected by epilepsy, and nearly 25% of patients cannot be treated effectively by available therapies. The presence of closed-loop seizure-triggered stimulation provides a promising solution for these patients. Realization of fast, accurate, and energy-efficient seizure detection is the key to such implants.(More)
Epileptogenesis, which occurs in an epileptic brain, is an important focus for epilepsy. The spectral analysis has been popularly applied to study the electrophysiological activities. However, the resolution is dominated by the window function of the algorithm used and the sample size. In this report, a temporal waveform analysis method is proposed to(More)
Playing a music instrument relies on the harmonious body movements. Motor sequences are trained to achieve the perfect performances in musicians. Thus, the information from audio signal is not enough to understand the sensorimotor programming in players. Recently, the investigation of muscular activities of players during performance has attracted our(More)
INTRODUCTION The aim of this study is to determine the effects and mechanisms of budesonide on angiogenesis in a murine asthma model. MATERIAL AND METHODS MURINE ASTHMA MODELS WERE ESTABLISHED AND MICE WERE DIVIDED INTO THREE GROUPS: the model group (OVA-sensitized and challenged mice), the BUD group (budesonide-treated mice) and the PBS group (normal(More)