Learn More
In this paper, an 8-channel closed-loop neural-prosthetic SoC is presented for real-time intracranial EEG (iEEG) acquisition, epileptic seizure detection, and adaptive feedback stimulation control. The SoC is composed of 8 energy-efficient analog front-end amplifiers (AFEAs), a 10b delta-modulated SAR ADC (DMSAR ADC), a configurable bio-signal processor(More)
AIMS Oxidative stress is implicated in the pathology of pulmonary arterial hypertension (PAH). Previously, we demonstrated that vardenafil, a phosphodiesterase-5 inhibitor, has potential as therapy for PAH, although the mechanism remained uncharacterized. Here, we aimed to determine baseline levels of oxidative stress in PAH and investigate whether(More)
OBJECTIVE To use a portable muscle tone assessment device to measure spasticity after a botulinum toxin type A (BTX-A) injection. DESIGN Before-after trial. SETTING Hospital. PARTICIPANTS Ten chronic stroke patients with upper-limb spasticity. INTERVENTION BTX-A was injected in the biceps brachii. MAIN OUTCOME MEASURES The biomechanic parameters,(More)
The development of many telemedicine systems focus on the utility of communication techniques. However, the comfort of long-term Electrocardiogram (ECG) monitoring in daily life is necessary and is also an important unresolved issue. A wearable mobile electrocardiogram monitoring system (WMEMS) is proposed to monitor ECG in this study. It mainly consists of(More)
OBJECTIVE To quantify changes of elbow spasticity over time after botulinum toxin type A (BTX-A) injection in the upper extremity of stroke patients. DESIGN Before-after trial in which the therapeutic effects were followed up at 2, 6, and 9 weeks after the BTX-A injection (Botox). SETTING Hospital. PARTICIPANTS Chronic stroke patients (N=8) with(More)
We hypothesized that three-dimensional pseudocontinuous arterial spin labelling (pCASL) may have similar efficacy in astrocytic tumour grading as dynamic susceptibility contrast-enhanced perfusion-weighted imaging (DSC-PWI), and the grading accuracy may be further improved when combined with apparent diffusion coefficient (ADC) values. Forty-three patients(More)
AIM Platinum agents have shown to be effective in the treatment of colorectal cancer. We assessed whether single nucleotide polymorphisms (SNPs) in GSTP1, ERCC1 Asn118Asn and ERCC2 Lys751Gln might predict the overall survival in patients receiving oxaliplatin-based chemotherapy in a Chinese population. METHODS SNPs of GSTP1, ERCC1 Asn118Asn and ERCC2(More)
It is critical to set up a precise and feasible monitoring system for a variety of animal and human studies. A multichannel wireless system for monitoring physiological signals of freely moving rats is presented. This system combines electroencephalogram (EEG) and acceleration signals, enabling the study of association between brain and behavior. A(More)
OBJECTIVE To observe the effect of diet-control only, diet-control with swimming training or with polysaccharide sulfate (PSS), a kind of blood lipid-lowering drug on the serum lipid level and vascular endothelial function in obese rats fed by fat-rich-diet. METHODS Forty Wistar rats were randomly divided into the following 5 groups: group F (n = 8),(More)