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Temozolomide (TMZ) is a novel cytotoxic alkylating agent for chemotherapy of malignant gliomas. However, intrinsic or acquired resistance to TMZ often defines poor efficacy of chemotherapy in malignant gliomas. A growing number of studies indicate that expression of O 6-methylguanine-DNA methyltransferase (MGMT) is one of the principal mechanisms(More)
OBJECTIVE To determine how early musculoskeletal disorders (MSDs) develop in dental professionals and to explore the potential differences among distinct dental specialties. MATERIAL AND METHODS 271 dental postgraduates majoring in five dental specialties were recruited, i.e., orthodontics, prosthodontics, endodontics, periodontics and alveolar surgery.(More)
Scientific and technical journals are considered vital media for the dissemination of scientific information. Currently, scientific editors are regarded as the primary business person for scientific journals. Therefore, the supervisory role of scientific editors is as an academic executor. The overdrafts and stressors derived from endless daily tasks can(More)
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