Yu. I. Pigolkin

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Fluorimetric methods were used to determine adrenaline, dopamine, noradrenaline, serotonin and tryptamine in the pia mater of the brain and spinal cord of various vertebrates (fishes, birds, mammals) and of man. The histochemical method using glyoxylic acid showed the presence of biogenic monoamines in adrenergic nerve fibres and in the monoaminocytes.(More)
The hypothesis was advanced [13-15], on the basis of data obtained as a result of pharmacological investigations, and was confirmed at the beginning of the 1980s [11, 23], that L-aspartate is an excitatory transmitter in the neurons of sensory systems of the PNS and the CNS. The amino acid is synthesized by aspartate aminotransferase (ASAT, EC: 2.6.1.1),(More)
In an immunochemical study of the melanocytes of the brain blood vessels in man, the presence of vasopressin has been demonstrated. The endings of cholinergic axons terminate on the surface of these cells. It is assumed that the melanocytes participate in regulation of the motility of the arteries of the brain.
29. J. Szentagotai, B. Flerco, B. Mess, and B. Halasz, Hypothalamic Control of the Anterior Pituitary, Budapest (1962). 30. H. Takeshita, Yonago Acta Med. 20, 125-141 (1976). 31. J .G. Veening, L. Swanson, and P. Sawchenko, Brain Res. 303, 337-357 (1984). 32. M. Velasco, Neuroendocrinology 10, 301-308 (1972). 33. J. Vitale and K. Gorski, Anat. Rec. 193,(More)
An original model of nephrogenic hypertension in rats was used for histochemical mapping of NADPH diaphorase (NO synthase) in various renal segments to examine the effect of hypotensive drugs furosemide, bendazol, and clonidine on the time course of nitroxide production in the kidneys. In various nephron segments, these drugs modulated NO synthesis in(More)
i. K. N. Veremeenko, Enzymes of Proteolysis and Their Inhibitors in Medical Practice [in Russian], Kiev (1971). 2. L. A. Lokshina, Mol. Biol., 13, No. 6, 1205 (1979). 3. L. A. Lokshina and E. A. Dilakyan, Mol. Biol., 20, No. 5, 1157 (1986). N. Back, Lancet, 2, 370 (1978). 4. D. A. Estell and M. Laskowski, Jr., Biochemistry, 19, 124 (1980). 5. H. Fritz and(More)
I. O. S. Adrianov, L. N. Molodkina, and N. G. Yamshchikova, Associative Brain Systems and Extrapolational Behavior [in Russian], Meditsina, Moscow (1987). 2. M. M. Aleksandrovskaya, F. A. Brozovskaya, Yu. Ya. Geinisman, et al., "Morphological rearrangement of neuroglia under conditions of intensified functioning of nervous cen~ers," Dokl. Akad. Nauk SSSR,(More)
Morphological criteria of the degree of innervation of arteries remain a debatable topic in histochemical investigations of vasomotor innervation. Until now, the absolute number or concentzation of vascular nerve fibers has generally been regarded as such a criterion [i, 2, 5]. However, the fact that transmitter secretion takes place only from varicosities(More)
The study of the adrenergic innervation of arteries of the human brain, as opposed to the animal brain, has not been undertaken on a wide scale. According to some workers [2, 3], comparable results can be achieved only if material taken a relatively short time after death is used. Not long ago the present writers [i] described the possibility Of(More)
The age-contingent characteristics of the cholinergic and adrenergic innervation of the cerebrovascular bed of mammals (Motavkin and Vlasov, 1976; Owman, 1979) have been studied quite comprehensively, as have the cholinergic (Osipova, 1973) and adrenergic neural appartuses of some of the major arteries of the brain in human beings (Edvinsson, Owman, and(More)
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