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RssAB-FlhDC-ShlBA as a Major Pathogenesis Pathway in Serratia marcescens
ABSTRACT Serratia marcescens has long been recognized as an important opportunistic pathogen, but the underlying pathogenesis mechanism is not completely clear. Here, we report a key pathogenesisExpand
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Murinization of Internalin Extends Its Receptor Repertoire, Altering Listeria monocytogenes Cell Tropism and Host Responses
Listeria monocytogenes (Lm) is an invasive foodborne pathogen that leads to severe central nervous system and maternal-fetal infections. Lm ability to actively cross the intestinal barrier is one ofExpand
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A mobile quorum-sensing system in Serratia marcescens.
Quorum-sensing systems that have been widely identified in bacteria play important roles in the regulation of bacterial multicellular behavior by which bacteria sense population density to controlExpand
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Pirin regulates pyruvate catabolism by interacting with the pyruvate dehydrogenase E1 subunit and modulating pyruvate dehydrogenase activity.
The protein pirin, which is involved in a variety of biological processes, is conserved from prokaryotic microorganisms, fungi, and plants to mammals. It acts as a transcriptional cofactor or anExpand
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Biochemical characterization of RssA-RssB, a two-component signal transduction system regulating swarming behavior in Serratia marcescens.
Our previous study had identified a pair of potential two-component signal transduction proteins, RssA-RssB, involved in the regulation of Serratia marcescens swarming. When mutated, both rssA andExpand
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PI3-kinase activation is critical for host barrier permissiveness to Listeria monocytogenes
Gessain et al. explore how Listeria monocytogenes facilitates disseminated infection through host epithelial barriers using two of its surface proteins, InlA and InlB. By combining in vitro and inExpand
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Activation of NK cell cytotoxicity by the natural compound 2,3‐butanediol
The natural compound 2,3‐BTD has diverse physiological effects in a range of organisms, including acting as a detoxifying product of liver alcohol metabolism in humans and amelioratingExpand
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The bacterial metabolite 2,3-butanediol ameliorates endotoxin-induced acute lung injury in rats.
Widely identified in bacteria, yeasts and human beings, 2,3-butanediol has been studied for decades. This chemical reportedly functions as a neutralization agent to counteract lethal acidification byExpand
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An iron detection system determines bacterial swarming initiation and biofilm formation
Iron availability affects swarming and biofilm formation in various bacterial species. However, how bacteria sense iron and coordinate swarming and biofilm formation remains unclear. Using SerratiaExpand
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RssAB Signaling Coordinates Early Development of Surface Multicellularity in Serratia marcescens
Bacteria can coordinate several multicellular behaviors in response to environmental changes. Among these, swarming and biofilm formation have attracted significant attention for their correlationExpand
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