Yu-Hsing Huang

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In this paper, an 8-channel closed-loop neural-prosthetic SoC is presented for real-time intracranial EEG (iEEG) acquisition, epileptic seizure detection, and adaptive feedback stimulation control. The SoC is composed of 8 energy-efficient analog front-end amplifiers (AFEAs), a 10b delta-modulated SAR ADC (DMSAR ADC), a configurable bio-signal processor(More)
The contribution of the zona incerta (ZI) of the thalamus on spike-wave discharges (SWDs) was investigated. Chronic recordings of bilateral cortices, bilateral vibrissa muscle, and unilateral ZI were performed in Long-Evans rats to examine the functional role of SWDs. Rhythmic ZI activity appeared at the beginning of SWD and was accompanied by(More)
PURPOSE Generalized absence seizures are characterized by bilateral spike-wave discharges (SWDs), particularly in the frontoparietal cortical region. In WAG/Rij and GAERS rats with absence epilepsy, recent evidence indicates that SWDs arise first from the lateral somatosensory cortex (LSC), that is, the cortical focus theory. To further understand the(More)
Epilepsy is one of the most common neurological disorders. Around 1% of the world’s population is affected, and nearly 25% of the patients cannot be treated by available therapies. Recently, seizure-triggered feedback electrical stimulation has been proved to effectively suppress pathological brain activities [1], but devices with accurate detection and(More)
The purpose of this study is to develop accident models that can be applied to modern road traflic. Several criteria are proposed that a model suitable for the conditions of modern road trafic should fulf; . Four commonly applied general accident models are reviewed and found to be inadequate in relation to the ci.iteria. Also, the consequences of an(More)
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