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We present the design and prototype of GnuStream, a peer-to-peer (P2P) and receiver-driven media streaming system. GnuStream is built on top of Gnutella, and it integrates dynamic peer location and streaming capacity aggregation. Each GnuStream streaming session is controlled by the receiver peer and involves a dynamic set of peer senders instead of one(More)
BACKGROUND Unaided attempts to quit smoking commonly fail during the first 2 weeks of the nicotine withdrawal syndrome. Alterations in dopamine (DA) signaling correlate with withdrawal from chronic nicotine exposure, but those changes have not been well-characterized. METHODS Mice were administered nicotine in their drinking water for 4 or 12 weeks. Then(More)
Tobacco smoking is a well-known risk factor for subsequent alcohol abuse, but the neural events underlying this risk remain largely unknown. Alcohol and nicotine reinforcement involve common neural circuitry, including the mesolimbic dopamine system. We demonstrate in rodents that pre-exposure to nicotine increases alcohol self-administration and decreases(More)
The aim of the present study was to determine the effects of low-level laser therapy (LLLT) on the homeostasis of reactive oxygen species (ROS) and expression of IGF-1 and TGF-β1 in the gastrocnemius muscles of rats following contusion. Muscle regeneration involves cell proliferation, migration, and differentiation and is regulated by growth factors. A(More)
In this paper, we propose an extension to current TCP protocol named concurrent TCP (cTCP), which can improve throughput of connections through balancing traffic load on multiple end-to-end paths. We keep the single-sliding-window architecture of TCP untouched for compatibility reasons. The two core components of the design are a packet scheduling switch(More)
SAMHD1 is the only known eukaryotic deoxynucleoside triphosphate triphosphohydrolase (dNTPase) and is a major regulator of intracellular dNTP pools. It has been reported to be a potent inhibitor of retroviruses such as HIV-1 and endogenous retrotransposons. Previous crystal structures have revealed that SAMHD1 is activated by dGTP-dependent tetramer(More)
Symbolic execution based test generation has made progress in recent years. However, in order to scale to larger programs there are some issues to be solved. Among them, generating a set of feasible paths to achieve high coverage gets more attention. In this paper, we focus on how to increase covering efficiency while maintaining high coverage. To achieve(More)
BACKGROUND The transplantation of limbal epithelial cells cultivated on amniotic membrane is a newly developed treatment for limbal stem cell deficiency. The purpose of our study was to investigate the biological characteristics of limbal epithelial cells and evaluate the effect of transplantation of cultivated human limbal epithelial cells on ocular(More)
In this paper, a quantum reinforcement learning method is proposed for repeated game theory. First, the quantum reinforcement learning algorithm is introduced based on quantum state superposition principle and its superiority is analyzed. Then, it is applied to repeated games and the experiments show its effectiveness. Related issues are also discussed(More)
At present, due to the growing attention focused on the issue of tendon-bone healing, we carried out an animal study of the use of genetic intervention combined with cell transplantation for the promotion of this process. Here, the efficacy of bone marrow stromal cells infected with bone morphogenetic protein-2 (BMP-2) on tendon-bone healing was determined.(More)