Effects of Infusion and Storage on Antioxidant Activity and Total Phenolic Content of Black Tea
This study determined antioxidant activity in terms of the 1,1-Diphenyl-2-picrylhydrazyl (DPPH) scavenging ability and total phenolic content of black tea under different infusion and storage…
Cytotoxic Sesterterpenoids from a Sponge Hippospongia sp.
The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues.
The Bioactive Extract of Pinnigorgia sp. Induces Apoptosis of Hepatic Stellate Cells via ROS-ERK/JNK-Caspase-3 Signaling
It appears that Pin leads to apoptosis in HSC-T6 cells through ROS-mediated ERK/JNK signaling and caspase-3 activation and pinnigorgiol A serves as a bioactive compound of Pin and may exhibit therapeutic potential by clearance of HSCs.
Isolation of marine bacteria with antimicrobial activities from cultured and field-collected soft corals
The results demonstrate that the marine bacteria from corals have great potential in the discovery of useful medical molecules.
Secondary Metabolites from the Soft Coral Sinularia arborea
Two new 13-hydroxycembrane diterpenoids, arbolides A and B, along with a known trihydroxysteroid, crassarosterol A, were isolated from the soft coral Sinularia arborea and Steroid 3 was found to exhibit cytotoxicity toward K562 and MOLT-4 leukemia.
Carijoside A, a Bioactive Sterol Glycoside from an Octocoral Carijoa sp. (Clavulariidae)
Carijoside A displayed significant inhibitory effects on superoxide anion generation and elastase release by human neutrophils and this compound exhibited moderate cytotoxicity toward DLD-1, P388D1, HL-60, and CCRF-CEM tumor cells.
1H NMR-Based Isolation of Anti-Inflammatory 9,11-Secosteroids from the Octocoral Sinularia leptoclados
Among the above-mentioned isolates, compound 4 had the most pronounced effect in inhibiting elastase release and superoxide anion generation, with the IC50 values of 2.96 and 1.63 μM, respectively.
Sterol constituents from a cultured octocoral Sinularia sandensis (Verseveldt 1977)
Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.
Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells and was elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues.
New 9-Hydroxybriarane Diterpenoids from a Gorgonian Coral Briareum sp. (Briareidae)
Six new 9-hydroxybriarane diterpenoids, briarenolides ZI–ZVI (1–6), were isolated from a gorgonian coral Briareum sp. The structures of briaranes 1–6 were elucidated by spectroscopic methods and by…