Yu-Che Cheng

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In this research we propose a fast and robust ellipse detection algorithm based on a multipass Hough transform and an image pyramid data structure. The algorithm starts with an exhaustive search on a low-resolution image in the image pyramid using elliptical Hough transform. Then the image resolution is iteratively increased while the candidate ellipses(More)
Cys2His2 zinc fingers are eukaryotic DNA-binding motifs, capable of distinguishing different DNA sequences, and are suitable for engineering artificial transcription factors. In this work, we used the budding yeast Saccharomyces cerevisiae to study the ability of tailor-made zinc finger proteins to activate the expression of the FLO11 gene, with phenotypic(More)
MOTIVATION Mass spectrometry is a high throughput, fast, and accurate method of protein analysis. Using the peaks detected in spectra, we can compare a normal group with a disease group. However, the spectrum is complicated by scale shifting and is also full of noise. Such shifting makes the spectra non-stationary and need to align before comparison.(More)
Candida albicans is an opportunistic human fungal pathogen. The ability to switch among multiple cellular forms is key to its pathogenesis. The Dbf4-dependent protein kinase gene CDC7 is conserved due to its role in initiating DNA replication. Because a C. albicans Cdc7 (Cacdc7) homozygous null was not viable, we generated a C. albicans strain with a(More)
A challenging problem in the wireless LAN localization is the severe fluctuation of the receive signal strength (RSS) even for the stationary client. The time-varying RSS which is resulted from the noise deteriorates the system accuracy drastically. Previous works presented various approaches to improve the positioning accuracy. Singular-Value-Decomposition(More)
Microfluidic devices provide low sample consumption, high throughput, high integration, and good environment controllability advantages. An alternative to conventional bioreactors, microfluidic devices are a simple and effective platform for stem cell investigations. In this study, we describe the design of a microfluidic device as a chemical and mechanical(More)
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