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A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
Combined analyses of gene networks and DNA sequence variation can provide new insights into the aetiology of common diseases that may not be apparent from genome-wide association studies alone.Expand
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Activation of PPARβ/δ inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release
The infiltration of PMNs into tissues is a prominent feature in inflammation. The mechanism underlying PMN recruitment depends on the release of chemotactic mediators and CAM expression onExpand
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Farnesoid X Receptor Ligands Inhibit Vascular Smooth Muscle Cell Inflammation and Migration
Objective—The farnesoid X receptor/bile acid receptor (FXR; NR1H4) is a ligand-activated transcription factor that regulates bile acid and lipid homeostasis, and is highly expressed in enterohepaticExpand
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