Youzhi Jiang

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Infection of the brain by lentiviruses, including human immunodeficiency virus (HIV) and feline immunodeficiency virus (FIV), causes inflammation and results in neurodegeneration. Molecular diversity within the lentivirus envelope gene has been implicated in the regulation of cell tropism and the host response to infection. Here, we examine the hypothesis(More)
Cytokines, including tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6), have been implicated in the pathogenesis of multiple sclerosis (MS). The production and release of these cytokines are regulated in part by specific purinergic (adenosine) cell surface receptors. To determine the extent to which the adenosine A1 receptor influenced(More)
The way is long with obstacles, I'm questing for the truth to and fro. iv Acknowledgments I would like to thank my advisor, Professor Ira Gessel, for his constant help and support, without which this work would never have existed. In this thesis, we enumerate different types of graphs in light of the combinatorial theory of species initiated by Joyal [13].(More)
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