Youyuan Wang

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Salivary Adenoid cystic carcinoma (SACC) patients with local invasion and lung metastasis are often resistant to conventional therapy such as operation, chemotherapy and radiotherapy. To explore the underling mechanisms, we studied the roles of miRNA in regulating invasiveness of SACC cells. MicroRNA profiling was done in SACC cells with microarray. MiRNA(More)
Epithelial-to-mesenchymal transition (EMT) is implicated in embryonic development and various pathological events. Transforming growth factor beta (TGFβ) has been reported to induce EMT in tumor cells, which is a critical step in the process of metastasis leading to cancer spreading and treatment failure. However, the involvement of microRNA during the EMT(More)
Cisplatin has been widely employed as a cornerstone chemotherapy treatment for a wide spectrum of solid neoplasms; increasing tumor responsiveness to cisplatin has been a topic of interest for the past 30 years. Strong evidence has indicated that mitochondrial fission participates in the regulation of apoptosis in many diseases; however, whether(More)
The demand of product design knowledge is complex and changeable, in order to solve the problem of how to efficiently obtain design knowledge demand, based on the analysis of context aware reasoning layer characteristics, constructs a context aware service system to obtain design knowledge needs. Bayesian method is used to design the knowledge category(More)
Condition Based Maintenance (CBM) scheduling for power equipment is based on some types of data in power system, such as the health condition of components, the load level of the substation and Life Cycle Cost (LCC), etc. Due to the lack of necessary data, traditional CBM strategy optimization models are usually established without enough data, and the(More)
The mechanism of thermogenesis and thermolysis of transformer was analyzed in this paper, the position of the hot-spot temperature was also analyzed. By calculating winding average surface temperature rising, a hot-spot temperature calculating model of dry -type transformer was established, and the calculating model of insulation life loss of dry-type(More)
Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cancer. Inducible nitric oxide synthase (iNOS) and p53 are associated with a variety of human cancers, but their expression and interaction in OSCC have not been fully explored. In this study, we investigated the expression of iNOS and p53 in OSCC and their correlation with tumor(More)
This paper studied the impact of moisture on the correlated characteristics of the condenser bushings oil-paper insulation system. The oil-impregnated paper samples underwent accelerated thermal aging at 130 ˝ C after preparation at different initial moisture contents (1%, 3%, 5% and 7%). All the samples were extracted periodically for the measurement of(More)