Young Ran Ha

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The parasite Plasmodium falciparum causes severe malaria and is the most dangerous to humans. However, it exhibits resistance to their drugs. Farnesyltransferase has been identified in pathogenic protozoa of the genera Plasmodium and the target of farnesyltransferase includes Ras family. Therefore, the inhibition of farnesyltransferase has been suggested as(More)
OBJECTIVES Utilisation of high-frequency drills is known to increase noise induced hearing loss due to increasing the damages of inner ear cells. This study aimed to investigate whether preconditioning by using dexmedetomidine (DEX) decreased the occurrence of ischemia in inner cells of the ear. METHODS We utilised a transgenic zebrafish line Brn3C, and(More)
Background Malaria is one of the world's public health problems in terms of medical emergency with a high risk of mortality. The protozoan malaria parasites are transmitted by infected female mosquitoes [1]. The most pathogenic human malaria parasite, Plasmodium falciparum, has gradually expanded in last three decades [2]. Choloroquine is the cheapest and(More)
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