Young Jae Kim

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BACKGROUND Assessment of Helicobacter pylori (H. pylori) clarithromycin resistance has rarely been performed routinely despite an increasing resistance rate. Our aim was to develop and evaluate the use of dual-priming oligonucleotide (DPO)-based multiplex polymerase chain reaction (PCR) to detect point mutations in the 23S rRNA gene responsible for(More)
OBJECTIVE To evaluate the clinicopathologic characteristics and prognostic factors of ovarian granulosa cell tumors. METHODS Medical records of 113 patients presenting between January 1995 and December 2007 were retrospectively reviewed. RESULTS One-hundred two patients had adult type disease, with a mean age of 46.2 years (range, 18 to 83 years) and a(More)
To investigate staging accuracy of MR for pancreatic neuroendocrine neoplasms (PNETs) and imaging findings according to the tumor grade. Our study consisted of 39 patients with PNET G1 (n = 24), PNET G2 (n = 12), and pancreatic neuroendocrine carcinoma (PNEC) (n = 3). All underwent preoperative MRI. Two radiologists retrospectively reviewed MR findings(More)
The identification of marker chromosomes is important for genetic counseling. However, the origin or composition can rarely be defined with conventional cytogenetic technique alone. In this study, we investigated the incidences and types of marker chromosomes in Korean patients and attempted to establish a cost-effective diagnostic approach for marker(More)
To assess therapeutic efficacy of gemcitabine and HIFU for a mouse model of pancreatic cancer, and the role of DCE-US for predicting early treatment response compared with pathology. In 48 PANC-1- nude mice (G1, HIFU_higher power [n = 14]; G2, gemcitabine [n = 12]; G3, combined gemcitabine and HIFU_low power [n = 12]; and G4, control [n = 10]), pulsed HIFU(More)
BACKGROUND There is an increasing need for the early detection of emerging mutations in the tyrosine-methionine-aspartate-aspartate (YMDD) motif of hepatitis B virus (HBV) DNA polymerase with using sensitive molecular methods. METHODS We evaluated the usefulness of monitoring lamivudine resistance using a matrix-assisted laser desorption/ionization(More)
Nucleic acid-based amplification tests allow the rapid detection of Mycobacterium tuberculosis. Recently, a real-time PCR assay for M. tuberculosis complex, the Cobas TaqMan MTB test (Roche Diagnostics, Basel, Switzerland), was introduced. We performed a prospective study to evaluate the diagnostic performance of the Cobas TaqMan MTB test system. A total of(More)
BACKGROUND This study was done to evaluate the effect on pain relief when acetaminophen was added to lidocaine for intravenous regional anesthesia (IVRA). METHODS SIXTY PATIENTS UNDERGOING HAND OR FOREARM SURGERY RECEIVED IVRA WERE ASSIGNED TO THREE GROUPS: Group C received 0.5% lidocaine diluted with 0.9% normal saline to a total volume of 40 ml (n =(More)
PURPOSE To maintain the homeostasis of stem cells and prevent their ability to initiate tumorigenesis, it is important to identify and modify factors that prevent or accelerate stem cell senescence. We used microarrays to attempt to identify such factors in human amniotic fluid (HAF)-derived stem cells. MATERIALS AND METHODS To identify gene expression(More)
PURPOSE To evaluate the differentiating factors for intraductal papillary mucinous neoplasm of the pancreas and chronic pancreatitis as determined by MR imaging. MATERIALS AND METHODS During a three-year period, we performed MR imaging on 33, consecutive patients with IPMN and on 41 patients with chronic pancreatitis. All IPMNs were confirmed by surgery.(More)