Youn Young Hur

Learn More
Peroxisome proliferator-activated receptor (PPAR) γ is known to be a key regulator of insulin resistance. PAM-1616 is a novel, non-thiazolidinedione small molecule compound synthesized in Dong-A Research Center. In this study, we characterized the pharmacological and safety profiles of PAM-1616 as a selective PPARγ modulator. PAM-1616 selectively binds to(More)
Fruit set is initiated only after fertilization and is tightly regulated primarily by gibberellins (GAs) and auxins. The application of either of these hormones induces parthenocarpy, fruit set without fertilization, but the molecular mechanism underlying this induction is poorly understood. In the present study, we have shown that the parthenocarpic fruits(More)
Expression of four peroxidase (POD) genes, three anionic PODs (swpa1, swpa2 and swpa3), and one neutral POD (swpn1) isolated from suspension cultures of sweet potato (Ipomoea batatas) were analyzed by measuring the accumulation of transcripts in suspension cultured cells and leaves of sweet potato in response to the stress-related plant hormones abscisic(More)
The concept that gibberellin (GA) application on seeded grapevines induces seedlessness has been known for decades in viticulture. GA was applied to inflorescence clusters of seeded diploid grapevine cultivar ‘Tamnara’ (Vitis spp.) at 14 days before full bloom (DBF). Morphological and molecular effects of GA application were examined on the induction of(More)
Lysyl-tRNA synthetase (KRS), a protein synthesis enzyme in the cytosol, relocates to the plasma membrane after a laminin signal and stabilizes a 67-kDa laminin receptor (67LR) that is implicated in cancer metastasis; however, its potential as an antimetastatic therapeutic target has not been explored. We found that the small compound BC-K-YH16899, which(More)
Dehydrins (DHNs) are proteins that are induced under dehydrating stress conditions such as drought, cold, and salinity. We investigated the expression of the DHN1 genes over time after drought treatment for 14 days and subsequent rehydration in the Korean native species, Vitis flexuosa, main cultivars ‘Campbell Early’ (Vitis spp.) and ‘Tamnara’ (Vitis(More)
Vitis flexuosa, a native Korean wild grapevine species, is more tolerant to abiotic stress than cultivated grapevines, but little is known about the mechanism underlying this tolerance. To better characterize the responses of V. flexuosa to drought stress and subsequent rehydration, we treated V. flexuosathe plants with four stress conditions: short- and(More)
  • 1