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DNA polymorphism is the basis to develop molecular markers that are widely used in genetic mapping today. A genome-wide rice (Oryza sativa) DNA polymorphism database has been constructed in this work using the genomes of Nipponbare, a cultivar of japonica, and 93-11, a cultivar of indica. This database contains 1,703,176 single nucleotide polymorphisms(More)
AIM To obtain the information of ligand-receptor binding between the S protein of SARS-CoV and CD13, identify the possible interacting domains or motifs related to binding sites, and provide clues for studying the functions of SARS proteins and designing anti-SARS drugs and vaccines. METHODS On the basis of comparative genomics, the homology search,(More)
College of Life and Environment Sciences (Y.-J.S., H.J., Z.-B.Z., G.W., C.W., Q.-B.Y., H.-J.L., D.-H.C., Z.-N.Y.) and Mathematics and Sciences College (J.-P.J., X.L., J.-H.G.), Shanghai Normal University, Shanghai 200234, China; College of Agricultural and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China (B.X.); Shanghai Information(More)
Brucellosis is a bacterial disease caused by Brucella infection. In the late fifties, Brucella suis vaccine strain S2 with reduced virulence was obtained by serial transfer of a virulent B. suis biovar 1 strain in China. It has been widely used for vaccination in China since 1971. Until now, the mechanisms underlie virulence attenuation of S2 are still(More)
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