Learn More
Besides the cytochrome c pathway, plant mitochondria have an alternative respiratory pathway that is comprised of a single homodimeric protein, alternative oxidase (AOX). Transgenic cultured tobacco cells with altered levels of AOX were used to test the hypothesis that the alternative pathway in plant mitochondria functions as a mechanism to decrease the(More)
Mitochondrial RNA (mtRNA) polymerases are related to bacteriophage RNA polymerases, but contain a unique amino-terminal extension of unknown origin and function. In addition to harboring mitochondrial targeting information, we show here that the amino-terminal extension of yeast mtRNA polymerase is required for a mtDNA maintenance function that is separable(More)
OBJECTIVES To assess the feasibility and safety of using the health-promoting traditional Chinese exercise, known as Baduanjin, in treating knee osteoarthritis (OA). SUBJECTS Twenty-eight (28) female patients who met the American College of Rheumatology criteria for osteoarthritis of the knee signed the informed consent and were randomized into the(More)
Aberrant microRNA (miRNA) expression is presently proposed to correlate with various human cancers and common single-nucleotide polymorphisms (SNP) at miRNA genes can influence the maturation of miRNAs or miRNA-mediated transcriptional regulation. However, whether miRNAs SNP alter gastric cancer susceptibility is still unclear. Here we investigated the(More)
Elucidating the mechanism underlying the poor proliferative capacity of adult pancreatic β-cells is critical to regenerative therapeutic approaches for diabetes. Here, we show that the microRNA (miR)-7/7ab family member miR-7a is enriched in mouse adult pancreatic islets compared with miR-7b. Remarkably, miR-7a targets five components of the mTOR signaling(More)
Epidemiologic findings are inconsistent concerning the association of endometrial cancer risk with alcohol consumption. Therefore, we conduct a meta-analysis of studies that assessed the association of alcohol consumption and the risk of endometrial cancer. A systematic literature search up to April 2010 was performed in MEDLINE and EMBASE, and(More)
Propagating trust/distrust from a set of seed (good/bad) pages to the entire Web has been widely used to combat Web spam. It has been mentioned that a combined use of good and bad seeds can lead to better results. However, little work has been known to realize this insight successfully. A serious issue of existing algorithms is that trust/distrust is(More)
OBJECTIVE To observe the early clinical outcomes of the internal fixation with distal radius volar locking compression plate (LCP) in treatment of distal clavicle fracture. METHODS Six patients with unilateral distal clavicle fractures, identified as type II according to Neer classification system, including 4 males and 2 females, were treated with open(More)
A large number of solutions have been proposed to support mobility in IP networks including original Mobile IP, its derivatives and several newly proposed protocols. However, these solutions have drawbacks in different aspects including triangle routing, handover inefficiency, heavy signaling overhead, etc. In this paper, we argue that these problems can be(More)
microRNAs (miRNAs) are non-coding small RNAs (sRNAs) capable of negatively regulating gene expression. Recently, microRNA-like small RNAs (milRNAs) were discovered in several filamentous fungi but not yet in Trichoderma reesei, an industrial filamentous fungus that can secrete abundant hydrolases. To explore the presence of milRNA in T. reesei and evaluate(More)