Yosuke Kuwahara

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The aim of the present study was to investigate the action of pituitary adenylate cyclase-activating polypeptide (PACAP) on ion transport in the guinea pig distal colon. Submucosal/mucosal segments from distal colon were mounted in Ussing flux chambers, and increases in short-circuit current (Isc) were used as an index of secretion. Serosal addition of(More)
In addition to performing general histology and cytology of the ciliary glands of the miniature pig, we studied the localization of glycoconjugates and beta-defensins in these glands with the use of carbohydrate histochemical and immunohistochemical methods. The secretory cells of the glands were equipped with non-homogeneous secretory granules, a(More)
Diabetes mellitus is associated with alterations in lipid metabolism and cardiac dysfunction despite an absence of coronary arteriosclerotic changes. To investigate mechanisms of cardiac dysfunction in diabetic cardiomyopathy, we studied the relation between activities of membrane-bound enzymes and surrounding phospholipids in rats with diabetes induced(More)
The aim of this study was to investigate compensatory lingual alveolar bone formation during tooth movement in young and old rats, using the vital bone marker tetracycline. Wistar male rats were separated into the following groups: 13-week-old rats without appliances (13C: control, n = 5), 60-week-old rats without appliances (60C: control, n = 5),(More)
1899年Angle1)は,第 一大臼歯 を咬合のkey とし,“old glory” の概念をかかげて,華 やか な咬合論を展開した。 さらに,不 正咬合の形態的 特徴 を上下顎歯列弓の前後的位置関係から表現 し た不正咬合の分類法を提唱 し,以 来Angleの 不 正咬合分類法として,矯 正学の分野で汎 く活用さ れ るに至った。 この方法に基い た分類の結果,ClassIが 最も 多 く1000人 中692人,ClassIII42人,そ して上 顎前突の大半 を占めると思われるClassIIは266 人で,26.6%を 占めていたとい う。 これに対 して高橋2)は,前 歯の咬合型から上顎 前突,下 顎前突,犬 歯低位唇側転位の不正咬合分 類法を発表した。この中で上下顎前歯の前後的被 蓋,す(More)
Repeated administration of histamine X 2HCl (40 mg/kg X 4) significantly augmented mepirizole (200 mg/kg) or cysteamine (300 mg/kg)-induced duodenal and gastric lesions in rats within 6 hr. Most of the duodenal lesions were penetrating ulcers and were located over the entire duodenum. Gastric lesions were mainly located in the antrum adjacent to the(More)
We examined the effect of human epidermal growth factor (hEGF) on the healing rate of gastric ulcers induced in rats. These ulcers were produced by a submucosal injection of 0.03 ml of 20% acetic acid into the stomach. Healing of the ulcers was delayed when a daily s.c. injection of indomethacin (1 mg/kg) was given for 4 wks. hEGF (100 and 300(More)
We examined the effects of orally administered human epidermal growth factor (hEGF) on healing of acetic acid-induced gastric ulcers in rats. hEGF, given twice daily at 30 and 100 micrograms/kg for 2 weeks or at 100 micrograms/kg for 4 weeks to rats with ulcers, had no effect on natural healing or the gastric secretion, delayed one caused by indomethacin.(More)
This article presents the orthodontic reconstruction of an adult bilateral cleft patient with a severe Class III malocclusion in which endosseous implants were inserted after secondary alveolar bone grafting. The patient was a 21-year-old Japanese male whose lateral incisors were congenitally missing and whose premaxilla was inclined lingually. The(More)
The aim of the study was to emphasize several specific functional aspects of the mammalian prostate gland. In this connection, the subcellular localization and characterization of glycoconjugates in the secretory epithelial cells were examined that line the prostate gland of the miniature pig, using cytochemistry, including lectin-gold methods. The results(More)