Yoshiya Katsura

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1 D iabetic retinopathy is characterized by increased vascular permeability, ischemia, and neovascularization. Ischemia in the retina can induce neovas-cularization via induction of vascular end o t h e l i a l g r o w t h f a c t o r (V E G F) expression by the transcription factor hy-poxia-inducible factor-1 (1). Hypoxia is also the main stimulus for(More)
PURPOSE We aimed to establish a novel screening system for identifying potential therapeutic agents for treating proliferative vitreoretinal diseases (PVDs). In this study, we focused on vitreous explants from chicken embryos and evaluated the usefulness of quantitatively analyzing the effects of potential candidates on cell-mediated vitreous contraction,(More)
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