• Publications
  • Influence
Endothelial lipase gene polymorphism is associated with acute myocardial infarction, independently of high-density lipoprotein-cholesterol levels.
BACKGROUND Endothelial lipase (EL) is a major determinant of high-density lipoprotein-cholesterol (HDL-C) metabolism and promotes monocytes recruitment. The local expression of EL could influenceExpand
  • 35
  • 11
Suppressive effect of the Gly389 allele of the beta1-adrenergic receptor gene on the occurrence of ventricular tachycardia in dilated cardiomyopathy.
Beta-1-adrenergic receptor (beta1-AR) blockers reduce both the incidence of sudden death and the ventricular volume in heart failure. In vitro, the Gly389 variant of beta1-AR mediates less adenylylExpand
  • 55
  • 5
Plasma levels of brain and atrial natriuretic peptides elevate in proportion to left ventricular end-systolic wall stress in patients with aortic stenosis.
Brain natriuretic peptide (BNP) is a novel cardiac hormone secreted predominantly from the ventricle. We examined the plasma levels of BNP and atrial natriuretic peptide (ANP) in 13 patients withExpand
  • 127
  • 2
Serotonin-2A receptor gene polymorphisms are associated with serotonin-induced platelet aggregation.
Masakatsu Shimizu, Kenji Kanazawa, Yasuaki Matsuda, Eiji Takai, Chikao Iwai, Yoshitomo Miyamoto, Masayoshi Hashimoto, Hozuka Akita*, Mitsuhiro Yokoyama Division of Cardiovascular and RespiratoryExpand
  • 19
  • 1
Xanthoma disseminatum with intracranial involvement: case report and literature review
Xanthoma disseminatum (XD) is a rare form of normolipemic mucocutaneous xanthomatosis of unknown etiology that is currently classified as a benign non-Langerhans cell histiocytosis. The disease isExpand
  • 14
  • 1
Sumatriptan provokes coronary artery spasm in patients with variant angina: possible involvement of serotonin 1B receptor.
BACKGROUND Serotonin (5HT) can induce coronary artery spasm (CAS) in patients with variant angina (VA). We have previously reported that 5HT(1B) and 5HT(2A) receptors gene were expressed in humanExpand
  • 13
  • 1
Arg389Gly polymorphism of the human beta1-adrenergic receptor in patients with nonfatal acute myocardial infarction.
BACKGROUND We sought to investigate the relation between the Arg389Gly polymorphism in the human beta1-adrenergic receptor (ADRB1) gene and acute myocardial infarction (AMI). It was previouslyExpand
  • 52
Serial changes in myocardial beta-adrenergic receptor after experimental brain death in dogs.
Early donor heart failure is one of the serious problems in heart transplantation. This heart failure may be related to myocardial change during brain death before implantation of the heart.Expand
  • 14
New methods to evaluate endothelial function: Non-invasive method of evaluating endothelial function in humans.
Evidence has accumulated that impairment of vascular endothelial function is the initial step in the development of atherosclerosis. One important finding is impairment of the release ofExpand
  • 29
High-grade neuroendocrine carcinoma of the lung presenting an unusual spread mimicking pleural mesothelioma associated with dermatomyositis.
Neuroendocrine tumors of the lung comprise a heterogeneous group of tumors that represents a spectrum of disease from typical carcinoid tumors to the high-grade neuroendocrine carcinomas (large-cellExpand
  • 9