Yoshito Yokoyama

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Portal vein embolization (PVE) improves outcome following major hepatectomy, and basic studies have presented evidence related to the mechanisms responsible for hepatic regeneration. Hemodynamic changes following PVE are similar to, but slightly different from, those of partial hepatectomy (PH) because arterial flow to the embolized lobe is preserved.(More)
Farrar’s criteria for cystic duct carcinoma (histopathologic diagnosis of a carcinoma strictly limited to the cystic duct) are impractical especially when making a diagnosis of primary cystic duct carcinoma in its advanced stage. Therefore, in our previous study, we proposed a new definition of cystic duct carcinoma: a gallbladder tumor, the center of which(More)
A Mongolian gerbil model was used to clarify whether long-term colonization by Helicobacter pylori is an important risk factor for the development of gastric cancer. Fifty-nine gerbils (3 controls and 56 gerbils inoculated with H. pylori) were killed at various times (average, 23 months) more than 12 months after H. pylori inoculation. In the H.(More)
Although the clinical data strongly suggest that Helicobacter pylori is associated with gastroduodenal diseases in humans, 1-3 there is no direct proof that these diseases are actually caused by H. pylori itself. Many animal models infected with H. pylori have already been studied to determine its pathogenesis, 4-1~ but none of these models mimics human H.(More)
In this study, to clarify whether Helicobacter pylori eradication alters the course of the development of gastric mucosal changes in the stomach, we examined the long-term effects of H. pylori eradication on H. pylori-inoculated gerbils. Methods: A total of 40 H. pylori-inoculated gerbils were randomized and subjected, at 22 months after inoculation, to(More)
Y-754, a novel benzimidazole compound, was investigated for in vitro and in vivo antibacterial activity. Unlike amoxicillin, clarithromycin, and metronidazole, the compound had no activity against common aerobic and anaerobic bacteria other than Helicobacter pylori. The minimum inhibitory concentration of Y-754 against H. pylori, at 0.025 microg/ml, was(More)
Y-904 is a new fluoroquinolone with a broad antimicrobial spectrum. In particular, it has anti- Helicobacter pylori activity superior to that of existing fluoroquinolones. In the present study it was examined for its in vitro antibacterial activity against 51 clinical isolates of H. pylori, including clarithromycin- and metronidazole-resistant strains. The(More)
Submicron-size particles of M-type Sr ferrite were obtained from fine Fe<inf>2</inf>O<inf>3</inf> and precipitated SrCO<inf>3</inf>. The magnetic properties of the powder were ¿<inf>s</inf>=71 emu/g and H<inf>cJ</inf>=5.5 kOe. The Hc<inf>J</inf> of the powder was reduced to less than 40% of its initial value by dry vibration milling. SEM observations showed(More)
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