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We examined whether fatty liver, as diagnosed with abdominal ultrasonography, is an independent risk factor for diabetes mellitus during 10 years of follow-up. A total of 840 subjects (467 men and 373 women) were followed for the entire 10 years. The criteria for being non-diabetic were having no history of diabetes, having a fasting plasma glucose level of(More)
Few studies have investigated the association between smoking and ultrasonographically diagnosed gallbladder (GB) disease, and their results were uncertain. This study was conducted to examine the association between smoking and drinking and GB diseases. A total of 9947 subjects (age, 30–69 years; 4953 men and 4994 women) voluntarily received a paid medical(More)
OBJECTIVE To investigate how weight cycling (gaining and losing weight) affects the risk of diabetes. DESIGN Cohort studies. SETTING Primary healthcare in urban and rural Japan. PARTICIPANTS 20 708 urban and 9670 rural residents. PRIMARY OUTCOME MEASURES ORs for diabetes in those with weight loss, weight loss-gain, stable weight, weight gain-loss(More)
OBJECTIVE The contributions of highly correlated cardiovascular risk factors to intraocular pressure (IOP) are not clear due to underlying confounding problems. The present study aimed to determine which metabolic syndrome parameters contribute to elevating IOP and to what extent. DESIGN Retrospective cohort study. SETTING A private healthcare centre in(More)
BACKGROUND Although obesity is a well-studied risk factor for diabetes, there remains an interest in whether "increasing body mass index (BMI)," "high BMI per se," or both are the actual risk factors for diabetes. The present study aimed to retrospectively compare BMI trajectories of individuals with and without diabetes in a case-control design and to(More)
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