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  • Tomoya Kawaguchi, Masashi Ando, +16 authors Akihito Kubo
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2014 (First Publication: 20 June 2014)
  • PURPOSE To investigate the efficacy of erlotinib versus docetaxel in previously treated patients with advanced non-small-cell lung cancer (NSCLC) in an epidermal growth factor receptor (EGFR)Expand
  • Yoshio Tomizawa, Hironobu Iijima, +11 authors Masatomo Mori
  • Medicine, Biology
  • Clinical Cancer Research
  • 2005 (First Publication: 1 October 2005)
  • Purpose: It has been reported that the mutations of epidermal growth factor receptor (EGFR) are detected in lung cancers. Studies of EGFR mutations in large numbers of patients' tumors with clinicalExpand
  • Michiho Nishioka, Takashi Kohno, +11 authors Jun Yokota
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2002 (First Publication: 3 September 2002)
  • Loss of heterozygosity on chromosome 22q has been detected in approximately 60% of advanced nonsmall cell lung carcinoma (NSCLC) as well as small cell lung carcinoma (SCLC), suggesting the presenceExpand
  • Yoshio Tomizawa, Toshiharu Nakajima, Takashi Kohno, Ryusei Saito, Naohito Yamaguchi, Jun Yokota
  • Biology, Medicine
  • Cancer research
  • 1998 (First Publication: 1 December 1998)
  • Abnormalities in structure and expression of the FHIT gene have been detected in a considerable fraction of primary lung tumors. Previous reports indicated that FHIT gene alterations can be simplyExpand
  • Tomoyuki Fujita, Masaharu Kiyama, Yoshio Tomizawa, Takashi Kohno, Jun Yokota
  • Biology, Medicine
  • International journal of oncology
  • 1999 (First Publication: 1 November 1999)
  • To date, the characteristics of p53 gene mutations in lung cancer have been extensively investigated. However, current estimates of p53 alterations are inaccurate, since most investigators haveExpand
  • Yoshio Tomizawa, Hironobu Iijima, +7 authors Masatomo Mori
  • Medicine
  • Lung cancer
  • 2004 (First Publication: 1 December 2004)
  • We investigated the clinicopathological significance of aberrant methylation of the retinoic acid receptor-beta2 (RARbeta2), RAS association domain family 1A (RASSF1A) and fragile histidine triadExpand