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BACKGROUND AND PURPOSE Voxel-based morphometry (VBM), used for detecting brain atrophy, permits comparison of local gray matter concentration at every voxel in an image between two groups. We sought to delineate the specific patterns of cerebral gray matter loss with regard to onset of Alzheimer's disease (AD) by using MR imaging and VBM and to evaluate the(More)
Review Abstract The urgent issues for automobile companies today are how to reduce the time and cost required for developing a new car. CAE (Computer Aided Engineering) has been regarded as an efficient way to solve these issues, and as a numerical experiment to replace prototypes and experiments. CAE was first introduced to reproduce phenomena that are(More)
BACKGROUND AND PURPOSE Three-dimensional imaging and hemispheric volumetry are useful for the assessment of degenerative cortical atrophy. Our purpose was to determine the features of cortical atrophy in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) by means of a hemispheric surface display generated with MR images. METHODS The(More)
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