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Familial hypertrophic cardiomyopathy (HCM) is a prevalent hereditary cardiac disorder linked to arrhythmia and sudden cardiac death. While the causes of HCM have been identified as genetic mutations in the cardiac sarcomere, the pathways by which sarcomeric mutations engender myocyte hypertrophy and electrophysiological abnormalities are not understood. To(More)
<italic>A highly parallel (more than a thousand) dataflow machine</italic> EM-4 <italic>is now under development. The</italic> EM-4 <italic>design principle is to construct a high performance computer using a compact architecture by overcoming several defects of dataflow machines. Constructing the</italic> EM-4, <italic>it is essential to fabricate a(More)
Packrat parsing is a powerful parsing algorithm presented by Ford in 2002. Packrat parsers can handle complicated grammars and recursive structures in lexical elements more easily than the traditional <i>LL(k)</i> or <i>LR</i>(1) parsing algorithms. However, packrat parsers require <i>O(n)</i> space for memoization, where <i>n</i> is the length of the(More)
Accumulating evidence indicates that TNFalpha plays an important role in the pathogenesis of periodontitis, but the effect of TNFalpha on the degradation of the periodontal ligament is not well understood. This study used reverse transcriptase-PCR to investigate the effects of TNFalpha on matrix metalloproteinase (MMP) mRNA expression in human periodontal(More)
In this paper, we present a thread-based programming model for the EM-4 hybrid dataflow machine, where parallelism and synchronization among threads of sequential execution are described explicitly by the programmer. Although EM-4 was originally designed as a dataflow machine, we demonstrate that it provides effective architectural support for a variety of(More)
The purpose of this study was to determine if the intraoral vertical ramus osteotomy is an effective treatment for anterior disk displacements with reduction and associated temporomandibular joint pain and dysfunction. Success with this procedure was predicated on producing a more functional articular disk-condyle relationship by anterior and inferior(More)
Latency tolerance is essential in achieving high performance on parallel computers for remote function calls and fine-grained remote memory accesses. EM-X supports interprocessor communication on an execution pipeline with small and simple packets. It can create a packet in one cycle, and receive a packet from the network in the on-chip buffer without(More)