Yoshinori Sugiyama

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Purification of fetal mouse hepatoblasts by magnetic beads coated with monoclonal anti-e-cadherin antibodies and their in vitro culture.

Miho Nitou, Yoshinori Sugiyama, Katsutoshi Ishikawa, Nobuyoshi Shiojiri
Experimental cell research
2002

A simple, rapid, and reproducible method of fetal hepatoblast purification was established to investigate mechanisms controlling interactions between hepatoblasts and nonparenchymal cells during… (More)

Involvement of aquaporin-7 in the cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells.

Mariko Hara-chikuma, Yoshinori Sugiyama, +5 authors Yoshiki Miyachi
FASEB journal : official publication of the…
2012

Dendritic cells (DCs) have the ability to present antigen and play a critical role in the induction of the acquired immune response. Skin DCs uptake antigen and subsequently migrate to regional… (More)

KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization.

Hiroyuki Yoshida, Aya Nagaoka, +8 authors Shintaro Inoue
Proceedings of the National Academy of Sciences…
2013

Hyaluronan (HA) has an extraordinarily high turnover in physiological tissues, and HA degradation is accelerated in inflammatory and neoplastic diseases. CD44 (a cell surface receptor) and two… (More)

Hyaluronan synthase 3 regulates hyaluronan synthesis in cultured human keratinocytes.

Tetsuya Sayo, Yoshinori Sugiyama, +5 authors Shintaro Inoue
The Journal of investigative dermatology
2002

Three human hyaluronan synthase genes (HAS1, HAS2, and HAS3) have been cloned, but the functional differences between these HAS genes remains obscure. The purpose of this study was to examine which… (More)

Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb.

Kazu Matsumoto, Yingcui Li, +8 authors Robert A. Kosher
Development
2009

The glycosaminoglycan hyaluronan (HA) is a structural component of extracellular matrices and also interacts with cell surface receptors to directly influence cell behavior. To explore functions of… (More)

A New Tobacco Mosaic Virus Vector and its Use for the Systemic Production of Angiotensin-I-Converting Enzyme Inhibitor in Transgenic Tobacco and Tomato

Hiroshi Hamamoto, Yoshinori Sugiyama, +5 authors Yoshimi Okada
Bio/Technology
1993

We have developed a new tobacco mosaic virus (TMV) RNA vector and have used it initially to systemically produce an angiotensin-I-converting enzyme inhibitor peptide (ACEI) in tobacco and tomato… (More)

Characterization of tight junctions and their disruption by UVB in human epidermis and cultured keratinocytes.

Takuo Yuki, Akira Hachiya, +7 authors Shintaro Inoue
The Journal of investigative dermatology
2011

It has not been confirmed whether tight junctions (TJs) function as a paracellular permeability barrier in adult human skin. To clarify this issue, we performed a TJ permeability assay using human… (More)

Preferential expression of connexin37 and connexin40 in the endothelium of the portal veins during mouse liver development

Nobuyoshi Shiojiri, Tohru Niwa, Yoshinori Sugiyama, Toru Koike
Cell and Tissue Research
2006

Hepatic blood vessels consist of the hepatic artery and three types of venous channels (the portal veins, the sinusoids, and the hepatic veins). This study was undertaken to analyze, by… (More)

Lutein, a nonprovitamin A, activates the retinoic acid receptor to induce HAS3-dependent hyaluronan synthesis in keratinocytes.

Tetsuya Sayo, Yoshinori Sugiyama, Shintaro Inoue
Bioscience, biotechnology, and biochemistry
2013

Carotenoids have been reported to have potent antioxidant activities and to protect tissues and cells from certain diseases and environmental insults. The molecular mechanism of the action of… (More)

Chemokine-dependent T cell migration requires aquaporin-3–mediated hydrogen peroxide uptake

Mariko Hara-chikuma, Shunsuke Chikuma, +4 authors Yoshiki Miyachi
The Journal of experimental medicine
2012

Chemokine-dependent trafficking is indispensable for the effector function of antigen-experienced T cells during immune responses. In this study, we report that the water/glycerol channel aquaporin-3… (More)

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