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Recent advances in biotechnology and the availability of ever more powerful computers have led to the formulation of increasingly complex models at all levels of biology. One of the main aims of systems biology is to couple these together to produce integrated models across multiple spatial scales and physical processes. In this review, we formulate a(More)
Recently, there have been demands for greater functional diversity and higher performance in the information technology infrastructure. As a result, the complexity and scale of product design in the product development phase have increased. In addition, development periods need to be reduced so products can be marketed sooner. These requirements have(More)
To understand the macroscopic function of the human heart based on sub-cellular microscopic events, multiscale analysis is indispensable. Our heart simulator uses the so-called homogenization method, where both the human heart and the myocardial cells are modeled and solved simultaneously by the finite element method. Because the contraction and deformation(More)
BACKGROUND Recent studies, supported by advances in computer science, have successfully simulated the excitation and repolarization processes of the heart, based on detailed cell models of electrophysiology and implemented with realistic morphology. METHODS In this study, we extend these approaches to simulate the body surface electrocardiogram (ECG) of(More)
We have developed the Grid Service Platform (GSP), which is a grid middleware for telecom carriers. GSP can support not only non-interactive batch style services, but also interactive real-time services. Moreover, GSP attains autonomous resource sharing between services based on the priority of each service. We conducted a field trial of GSP on a testbed(More)