Yoshikuni Sato

  • Citations Per Year
Learn More
Digital holographic microscopy (DHM) is a well-known powerful method allowing both the amplitude and phase of a specimen to be simultaneously observed. In order to obtain a reconstructed image from a hologram, numerous calculations for the Fresnel diffraction are required. The Fresnel diffraction can be accelerated by the FFT (Fast Fourier Transform)(More)
Serious vaccine-associated adverse events are rare. To further minimize their occurrence and to provide adequate care to those affected, careful monitoring of immunization programs and case management is required. Unfounded vaccine safety concerns have the potential of seriously derailing effective immunization activities. To address these issues, vaccine(More)
Antisense technology provides an effective strategy to inhibit synthesis of the gene product. We prepared a novel antisense reagent comprised of oligodeoxynucleotides (ODN) and a thermo responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm). The conjugate inhibited gene expression in a dose-dependent manner. The ODN-PNIPAAm conjugate demonstrated(More)
The loss-of-function mutation in the RB tumor suppressor gene at tumor initiation occurs in surprisingly few types of cancer. The inactivation of the RB product is often found during the progression of common types of cancers including prostate, breast, bladder, and esophageal cancers [1]. Most canonical function of pRB is to control cell proliferation that(More)
The learning of evaluation functions from game records has been widely studied in the field of computer game-playing. Conventional learning methods optimize the evaluation function parameters by using the game records of expert players in order to imitate their plays. Such conventional methods utilize objective functions to increase the agreement between(More)
  • 1