Yoshiko Toyoda

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OBJECTIVES/HYPOTHESIS Cholesteatomas are epidermal inclusion cysts containing stratified squamous epithelium that arise in the middle ear and mastoid cavities resulting in a persistent inflammatory state. Complications include chronic otorrhea, granulation tissue, and bony erosion. Cholesteatoma growth patterns predict frequent involvement of the Fallopian(More)
vascularity. 1 Adjunctive measures have included free micro-vascular transfer, supercharging, caspase inhibitors and free oxygen radical scavengers. In this study, we explored the potential complementary effects of HBOT and stem cell delivery on cutaneous flap survival. MATERIALS AND METHODS: The potential healing benefits of HBOT preconditioning and(More)
Non-thermal plasma has become an increasingly useful technology across a wide variety of disciplines. Currently a number of plasma-based technologies, which deliver reactive oxygen and nitrogen species (RONS), are being investigated for therapeutic sterilization in the biomedical field. We report on a novel, non-thermal plasma/free radical system developed(More)
SELEX, the process of selecting aptamers, is often hampered by the difficulty of preparing target molecules in their native forms and by a lack of a simple yet quantitative assay for monitoring enrichment and affinity of reactive aptamers. In this study, we sought to discover DNA aptamers against human serum markers for potential therapeutic and diagnostic(More)
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