Yoshiko Toyoda

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OBJECTIVES/HYPOTHESIS Cholesteatomas are epidermal inclusion cysts containing stratified squamous epithelium that arise in the middle ear and mastoid cavities resulting in a persistent inflammatory state. Complications include chronic otorrhea, granulation tissue, and bony erosion. Cholesteatoma growth patterns predict frequent involvement of the Fallopian(More)
Non-thermal plasma has become an increasingly useful technology across a wide variety of disciplines. Currently a number of plasma-based technologies, which deliver reactive oxygen and nitrogen species (RONS), are being investigated for therapeutic sterilization in the biomedical field. We report on a novel, non-thermal plasma/free radical system developed(More)
SELEX, the process of selecting aptamers, is often hampered by the difficulty of preparing target molecules in their native forms and by a lack of a simple yet quantitative assay for monitoring enrichment and affinity of reactive aptamers. In this study, we sought to discover DNA aptamers against human serum markers for potential therapeutic and diagnostic(More)
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