Yoshiko Takai

Learn More
PURPOSE We set out to determine whether morphological retinal changes occur in patients with acute zonal occult outer retinopathy (AZOOR). METHODS Five patients diagnosed with AZOOR were studied. They included two men and three women, with an age range of 23-51 years. Symptoms and findings were retrospectively and prospectively collected. The(More)
PURPOSE To determine whether an intravitreal injection of bevacizumab alters the concentration of vascular endothelial growth factor (VEGF) in the aqueous humor of eyes with retinopathy of prematurity. METHODS Seven Stage 4 and three Stage 5 eyes of eight patients with retinopathy of prematurity were studied. Bevacizumab (0.75 mg/0.03 mL/eye) was injected(More)
 In smooth muscle cells freshly isolated from the bovine ciliary body, effects of carbachol (CCh) on the membrane potential and current were examined by the whole-cell clamp method. The resting membrane potential of the muscle cells used was –60 ± 1 mV (n=111). Extracellular application of CCh (2 μM) depolarized the cells to –15 ± 5 mV (n=50) with an(More)
PURPOSE To describe the clinical findings and surgical results of superior oblique palsy with class III tendon anomaly. DESIGN Observational case series. METHODS One hundred and forty-one cases of congenital and idiopathic superior oblique palsy were operated on by one surgeon (M.S.) between September 1, 1995 and August 31, 2007. The superior oblique(More)
To investigate the development of stereoscopic acuity (stereoacuity) in children longitudinally. Seven full-term normal infants whose age at the beginning of the study was between 12 and 23 weeks were studied. A computer-based random-dot test of stereoscopic vision (TV-Random Dot Stereo Test) was used to measure stereoacuity. The test was repeated at 2- to(More)
To evaluate the refractive characteristics of adults diagnosed with retinopathy of prematurity (ROP) treated with ablation treatment as children, we measured best corrected visual acuity (BCVA, logMAR), spherical equivalent refraction (SER), axial length (AL), lens thickness (LT), anterior chamber depth (ACD) and the corneal curvature radius (CCR) from 46(More)
In the ciliary muscle, the tonic contraction requires a sustained influx of Ca2+ through the cell membrane. However, little has hitherto been known about the route(s) of Ca2+ influx in this tissue that lacks voltage-gated Ca2+ channels. To identify ion channels as the Ca2+ entry pathway we studied the effects of carbachol (CCh) on freshly isolated bovine(More)
BACKGROUND AND PURPOSE To describe four cases of functional visual loss which challenge the theory that its causes are different in children and adults (i.e., that financial gain is the primary cause in adults while in children it is an involuntary response to psychosocial problems). Rather, we will show a similar etiology of functional visual loss in(More)
over his left temple on left gaze. He did not have any visual disturbance, but reported an occasional loss of consciousness and a floating sensation. His medical history included measles at 8 months of age. At the first examination, his visual acuity was 1.5 in both eyes (OU). The findings in the slit-lamp examination were normal but ophthalmoscopy showed a(More)
PURPOSE To report a case of uveitis associated with juvenile idiopathic arthritis that progressed from iritis to panuveitis with disc neovascularization during a clinical trial of etanercept, a tumor necrosis factor a (TNF-alpha) blocker. CASE A 12-year-old girl with juvenile idiopathic arthritis, which had begun at the age of 1 year 7 months. The patient(More)