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Human cathelicidin CAP18/LL-37 changes mast cell function toward innate immunity.
- M. Yoshioka, N. Fukuishi, +8 authors M. Akagi
- Biology, Medicine
- Biological & pharmaceutical bulletin
- 1 February 2008
The antimicrobial peptide LL-37 is generated from skin keratinocytes during infection of Gram-negative bacteria and exerts a microbicidal effect. LL-37 also causes functional changes in mast cells.… Expand
Bacterial components regulate the expression of Toll-like receptor 4 on human mast cells
Abstract.Objectives and design:The aim of this study was to investigate whether the exposure of mast cells (MCs) to bacterial components affects the expression of Toll-like receptor (TLR) 4, and to… Expand