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Disturbed lipid metabolism in patients with subclinical hypothyroidism: effect of L-thyroxine therapy.

• Shinichi Miura, Makoto Iitaka, +7 authors Kunihiko Ito
• Internal medicine
• 1994

To evaluate whether patients with subclinical hypothyroidism have a disturbance in lipid metabolism, and whether supplemental L-thyroxine (L-T4) therapy would improve their lipid parameters, we… (More)

Decrease in serum levels of thyroid hormone in patients with coronary heart disease.

• Shinichi Miura, Makoto Iitaka, +10 authors Jun Ishii
• Endocrine journal
• 1996

The aim of this study was to evaluate the relationship between subclinical hypothyroidism and/or autoimmune thyroid disease and coronary heart disease (CHD). Ninety seven patients diagnosed as having… (More)

The effect of xenotransplantation of human thyroid tissue following radioactive iodine-induced thyroid ablation on thyroid function in the nude mouse.

• Yasushi Kasuga, Shigeru Matsubayashi, Yoshiki Sakatsume, Fumito Akasu, Catriona Jamieson, Rich Volpe
• Clinical and investigative medicine. Medecine…
• 1991

We have attempted to determine whether xenotransplanted human thyroid tissue into nude mice would act as a physiological substitute for the mouse thyroid gland after the mice had been rendered… (More)

Nontoxic nodular goiter and papillary thyroid carcinoma are not associated with peripheral blood lymphocyte sensitization to thyroid cells.

• J F Aguayo, Yoshiki Sakatsume, Catriona Jamieson, VasV. Row, Rich Volpe
• The Journal of clinical endocrinology and…
• 1989

We tested the claim that uni- and multinodular goiter (UNG and MNG) and papillary carcinoma (PC) of the thyroid are autoimmune thyroid diseases (AITD) similar to Graves' disease (GD) and Hashimoto's… (More)

Effects of recombinant human interferon gamma on human thyroid tissues from patients with Graves' disease and normal subjects transplanted into nude mice.

• Yasushi Kasuga, Shigeru Matsubayashi, Yoshiki Sakatsume, Norman Fritz Miller, Catriona Jamieson, Rich Volpe
• Journal of endocrinological investigation
• 1990

We have attempted to determine whether interferon gamma (IFN gamma) would enhance, sustain or induce autoimmune thyroid disease (AITD) in xenotransplanted thyroid tissue from patients with Graves'… (More)

Decreased serum thyroglobulin levels in the late stage of pregnancy.

• Yoshihito Hara, Toshinori Tanikawa, +5 authors Yoichi Murayama
• Acta endocrinologica
• 1986

Serum thyroglobulin levels were serially measured in 25 normal pregnant women to evaluate thyroidal activity during normal pregnancy. Measurements included serum T3, T4, free T4, TBG, and TSH. Tg and… (More)

CD4 cells from patients with autoimmune thyroid disease secrete interferon gamma after stimulation by thyroid microsomal antigen; CD8 cells suppress this secretion.

• Yoshiki Sakatsume, Shigeru Matsubayashi, Yasushi Kasuga, Makoto Iitaka, Yoshinori Iwatani, Rich Volpe
• Journal of endocrinological investigation
• 1990

The production of interferon gamma (IFN gamma) by peripheral blood mononuclear cells (PBMC) from normal persons and patients with autoimmune thyroid disease (AITD) has been studied in vitro either… (More)

Serum interferon gamma levels in autoimmune thyroid disease.

• Shigeru Matsubayashi, Yasushi Kasuga, Yoshiki Sakatsume, Fumito Akasu, Rich Volpe
• Clinical and investigative medicine. Medecine…
• 1990

The lymphokine, interferon gamma (IFN gamma) is considered to play an important role in the development of autoimmune thyroid disease (AITD); the main source of IFN gamma has been shown to be CD4… (More)

The mechanism for the discrepancy between serum total and free thyroxine values induced by autoantibodies: report on two patients with Graves' disease.

• Makoto Iitaka, Naoki Fukasawa, +5 authors Jun Ishii
• Acta endocrinologica
• 1990

The sera from two patients with Graves' disease gave abnormally high serum free T4 values as compared with the total T4 and other hormone values, suggesting the presence of autoantibodies to labelled… (More)

Lack of response of peripheral blood mononuclear cells to thyroid microsomal antigen in nontoxic nodular goiters.

• Yoshiki Sakatsume, Shigeru Matsubayashi, Yasushi Kasuga, Rich Volpe
• Regional immunology
• 1990

The production of interferon gamma (IFN gamma) by peripheral blood mononuclear cells (PBMC) from patients with nontoxic nodular goiter (NTNG), autoimmune thyroid disease (AITD), and normal persons… (More)

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