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Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light
Our eyes are increasingly exposed to light from the emitting diode (LED) light of video display terminals (VDT) which contain much blue light. VDTs are equipped with televisions, personal computers,Expand
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Nrf2 protects photoreceptor cells from photo‐oxidative stress induced by blue light
ABSTRACT Oxidative stress plays a key role in age‐related macular degeneration and hereditary retinal degenerations. Light damage in rodents has been used extensively to model oxidativeExpand
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The potential neuroprotective effect of human adipose stem cells conditioned medium against light-induced retinal damage.
Human adipose-derived stem cells (hASCs) are present in adult adipose tissue and have been reported to secrete various factors that have neuroprotective effects. In the present study, we examinedExpand
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Photobiomodulation with 670 nm light increased phagocytosis in human retinal pigment epithelial cells
Purpose Photobiomodulation is the treatment with light in the far-red to near-infrared region of the spectrum and has been reported to have beneficial effects in various animal models of disease,Expand
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Exposure to excessive blue LED light damages retinal pigment epithelium and photoreceptors of pigmented mice
&NA; To determine the characteristics of the damages of the retinal pigment epithelium (RPE) and photoreceptors of pigmented mice induced by exposure to blue light emitting diode (LED) light, and toExpand
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Progranulin promotes the retinal precursor cell proliferation and the photoreceptor differentiation in the mouse retina
Progranulin (PGRN) is a secreted growth factor associated with embryo development, tissue repair, and inflammation. In a previous study, we showed that adipose-derived stem cell-conditioned mediumExpand
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Colored lenses suppress blue light-emitting diode light-induced damage in photoreceptor-derived cells
Abstract. Blue light-emitting diodes (LEDs) in liquid crystal displays emit high levels of blue light, exposure to which is harmful to the retina. Here, we investigated the protective effects ofExpand
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The Involvement of the Oxidative Stress in Murine Blue LED Light-Induced Retinal Damage Model.
The aim of study was to establish a mouse model of blue light emitting diode (LED) light-induced retinal damage and to evaluate the effects of the antioxidant N-acetylcysteine (NAC). Mice wereExpand
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Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro
BackgroundBlue light is a high-energy or short-wavelength visible light, which induces retinal diseases such as age-related macular degeneration and retinitis pigmentosa. Bilberry (VacciniumExpand
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Astaxanthin analogs, adonixanthin and lycopene, activate Nrf2 to prevent light-induced photoreceptor degeneration.
Carotenoids, in particular astaxanthin, possess potent antioxidant capabilities. Astaxanthin also induces NF-E2-related factor 2 (Nrf2), which plays a major regulatory role in the antioxidativeExpand
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