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I.ntegrin/hgand binding evokes tyrosine phosphorylation of various proteins. We reported previously that a 105 kD protein (ppl05) was tyrosine phosphorylated by the engagement of [31 integrins in T lymphocytes. We show here that ppl05 is a novel p130Cas (Crk-associated substrate)-related protein. Deduced amino acid sequence revealed that ppl05 contains(More)
In the three-phase liquid-membrane system consisting of water-nitrobenzene-water, the decrease in pH of aqueous phases is found to be accompanied with the spontaneous electric oscillation of several modes. The increase rates of proton concentration in each aqueous phase are found to differ considerably in each modes of electric oscillation. Furthermore, the(More)
Hypothesis / aims of study Oral rebamipide has been used for treatment of gastritis and ulcer disease. Local application of rebamipide is effective treatment for the tissue injuries in the colon, lungs, kidneys, liver, and cornea in animal models, and it was recently approved for treating dry eye in Japan. Because the mechanism of action of rebamipide(More)
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