Yoshihisa Nagai

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Tissue factor pathway inhibitor (TFPI) is a heparin-binding protein involved in the extrinsic blood coagulation system. In order to elucidate the minimal size of heparin chain required for the interaction with TFPI, we prepared a series of heparin-derived oligosaccharides with tailored chain length ranged from disaccharide to eicosasaccharide after the(More)
The emphasis laid by glycobiologists on cell adhesion in terms of carbohydrate interaction is now shifted to the aspects where the interaction is associated with the regulation of various cellular activities via biosignalling and glycosphingolipids, in particular, gangliosides (sialic acid-containing glycosphingolipids) play an important functional role.(More)
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