Yoshihisa Fukushima

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BACKGROUND AND PURPOSE Diabetes mellitus is an established risk factor for stroke. However, it is uncertain whether prestroke glycemic control (PSGC) status affects clinical outcomes of acute ischemic stroke. The aim of this study was to elucidate the association between PSGC status and neurological or functional outcomes in patients with acute ischemic(More)
We report a 50-year-old woman with systemic lupus erythematosus (SLE) who developed stroke-like symptoms, including disturbance of consciousness and severe left hemiparesis. Despite the stroke-like symptoms, MR imaging showed quite atypical findings for stroke; broad high-intensity areas in the right fronto-parietal lobes on diffusion-weighted images were(More)
A 40-year-old man who presented with left hemiparesis was admitted to our hospital. He had tachycardia and a fever. He had a 25-year history of insulin therapy for diabetes mellitus. Brain magnetic resonance (MR) images showed fresh infarction in the right hemisphere, and carotid ultrasonography showed stenosis of the right internal carotid artery (ICA). We(More)
The aim of this study was to assess the efficacy, safety, and concentration of meropenem in cerebrospinal fluid when meropenem (2 g every 8 h) was administered to Japanese adult patients with bacterial meningitis. Five Japanese patients (mean age 60.6 years [range 35-71]) were enrolled. Infection with Streptococcus pneumoniae (three patients), Streptococcus(More)
The clinical course was investigated of 137 epileptic patients who had been under continuous observation and therapy for the past 11 to 23 years. When a remission of epilepsy was defined as a seizure-free period for three years and a relapse was defined as an occurrence of seizures after the remission, the remission rate was 45%, but 32% of the subjects had(More)
Herpes simplex encephalitis (HSE) has come to be widely recognized as diagnosable and treata‐ ble at early stages of the disease. The incidence of encephalitis/encephalopathy resulting from other members of herpesvirus group such as varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus (HHV)-6 has also tended(More)
BACKGROUND Among patients with ischemic stroke and atrial fibrillation, which ones are at high risk of recurrent stroke is unclear. This study aimed to determine whether left atrial size was associated with long-term risk of stroke recurrence in patients with nonvalvular atrial fibrillation. METHODS AND RESULTS In this multicenter prospective cohort(More)