Learn More
There is increasing evidence that heparan sulfate (HS) plays an essential role in various axon guidance processes. These observations, however, have not addressed whether HS is required cell autonomously as an axonal coreceptor or as an environmental factor that modulates the localization of guidance molecules in the terrain in which growing axons navigate.(More)
In the Toshiba software factory, quality control and productivity improvements are primary concerns. Emphasis is placed on reusing existing software modules that have been proven correct through actual operation. To achieve a substantial degree of reuse, the software design process is viewed at several levels of abstraction. In this paper, these levels of(More)
We study the extent to which vibrotactile stimuli delivered to the head of a subject can serve as a platform for a brain computer interface (BCI) paradigm. Six head positions are used to evoke combined somatosensory and auditory (via the bone conduction effect) brain responses, in order to define a multimodal tactile and auditory brain computer interface(More)
Development of the mammalian central nervous system proceeds roughly in four major steps, namely the patterning of the neural tube, generation of neurons from neural stem cells and their migration to genetically predetermined destinations, extension of axons and dendrites toward target neurons to form neural circuits, and formation of synaptic contacts.(More)
A brain-computer interface (BCI) is a technology for operating computerized devices based on brain activity and without muscle movement. BCI technology is expected to become a communication solution for amyotrophic lateral sclerosis (ALS) patients. Recently the BCI2000 package application has been commonly used by BCI researchers. The P300 speller included(More)
We propose a method for an improvement of auditory BCI (aBCI) paradigm based on a combination of ASSR stimuli optimization by choosing the subjects' best responses to AM-, flutter-, AM/FM and click-envelope modulated sounds. As the ASSR response features we propose pairwise phase-locking-values calculated from the EEG and next classified using binary(More)
The study presented explores the extent to which tactile stimuli delivered to the ten digits of a BCI-naive subject can serve as a platform for a brain computer interface (BCI) that could be used in an interactive application such as robotic vehicle operation. The ten fingertips are used to evoke somatosensory brain responses, thus defining a tactile brain(More)
Although various methods and techniques for managing the mass production and quality control of software products have been developed, a majority of existing software factories have adopted the modular approach to program development and testing. 1-6 Indeed, this approach has become fundamental to large systems software factories mainly because practical(More)