Yoshihiro Kosaka

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Tissue-engineered vascular autografts (TEVAs) were made by seeding 4-6 x 10(6) of mixed cells obtained from femoral veins of mongrel dogs onto tube-shaped biodegradable polymer scaffolds composed of a polyglycolid acid (PGA) nonwoven fabric sheet and a copolymer of L-lactide and caprolactone (n = 4). After 7 days, the inferior vena cavas (IVCs) of the same(More)
Identification of an isolated tumour cell with metastatic ability is important for predicting the recurrence and prognosis of gastric cancer. A biological marker for evaluating the metastatic ability of gastric cancer cells has not yet been identified. We assessed vascular endothelial growth factor receptor-1 mRNA expression by quantitative real-time(More)
Urokinase-type plasminogen activator receptor (uPAR) plays a central role in the plasminogen activation cascade and participates in extracellular matrix degradation, cell migration and invasion. We evaluated the expression level of uPAR mRNA and the presence of isolated tumour cells (ITCs) in bone marrow (BM) and peripheral blood (PB) in gastric cancer(More)
This study was performed to investigate the effect of fentanyl alone on heart rate variability (HRV) during mechanical ventilation using power spectral analysis. Arterial baroreceptor reflex was also tested with pharmacological manipulation to assess the contribution of vagal baroreceptor reflex modulation of HRV during fentanyl anesthesia. Ten patients(More)
We evaluated the postoperative pain relief and side-effects of continuous epidural infusion of three analgesic regimens following major thoracic and/or abdominal surgery. One hundred and twenty patients were randomly divided into three treatment groups: (1) 0.25% or 0.5% bupivacaine at a rate of 3–7 ml·hr−1, (2) 0.01% morphine at a rate of 1–2 ml·hr−1, (3)(More)
To determine whether spontaneous respiration is suitable for frequency domain analysis of heart rate (R-R interval) variability, we studied 15 volunteers (5 men and 10 women, aged 22–34 years) and evaluated the reproducibility of the power spectrum. Electrocardiograms were recorded for 5 min each with spontaneous and rate-controlled respiration (15(More)
Purpose. We investigated the effect of nitroglycerin(NTG) on fractal features of short-term heart rate variability (HRV) and blood pressure variability (BPV) using coarse-graining spectral analysis (CGSA). Method. Nine healthy young volunteers participated in this study. Five-minute recordings of electrocardiogram and blood pressure estimated by(More)
Porphyrias are inherited or acquired disturbances in heme synthesis, and are usually divided into two main groups, erythropoietic and hepatic, according to the two major sites of heine synthesis [1]. Among hepatic porphyrias, acute intermittent porphyria (AIP), variegate porphyria (VP), and hereditary coproporphyria (HCP) may give rise to an acute attack(More)
This paper explores a method for creating large-scale urban 3D models using Historical GIS data. The method is capable of automatically generating realistic VR models based on GIS data at a low cost. 3D models of houses are created from polygon data, fences from line data, and pedestrians and trees from point data. The method is applied to the Virtual Kyoto(More)
Recent advance in ubiquitous technology has led the development of ubiquitous sensor environment in which various kinds of sensor devices provide sensor data. In this environment, since an enormous number of sensor devices join the network, it is effective to construct a P2P network for efficient retrieval of sensor data. In general, each sensor device(More)