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Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects

• Rika Aizawa, Takashi Kanbayashi, +6 authors Tetsuo Shimizu
• Psychiatry and clinical neurosciences
• 2002

Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. The present study evaluated the effects of YKCH on sleep by all-night polysomnography using… (More)

Diazepam reduces both arterial blood pressure and muscle sympathetic nerve activity in human

• Tsuyoshi Kitajima, Takashi Kanbayashi, +6 authors Tetsuo Shimizu
• Neuroscience Letters
• 2004

It is known that benzodiazepines have a hypotensive effect, but the mechanism has not been well elucidated yet. To clarify whether this effect is due to central or peripheral mechanism, we… (More)

Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects.

• Takashi Kanbayashi, Tomonari Sugiyama, +6 authors Tetsuo Shimizu
• Psychiatry and clinical neurosciences
• 2002

Donepezil (Aricept) is a therapeutic drug for the treatment of Alzheimer's disease (AD). However, there have been only two reports describing the effects of donepezil on sleep as assessed by… (More)

Alcohol has a dose-related effect on parasympathetic nerve activity during sleep.

• Yohei Sagawa, Hideaki Kondo, +6 authors Tetsuo Shimizu
• Alcoholism, clinical and experimental research
• 2011

BACKGROUND The aim of this study was to identify the acute effects of ethanol on the relationship between sleep and heart rate variability (HRV) during sleep. METHODS Ten healthy male university… (More)

Diazepam binding inhibitor (DBI) gene expression in the brains of socially isolated and group-housed mice

• Erbo Dong, Kinzo Matsumoto, Michihisa Tohda, Yoshihiko Kaneko, Hiroshi Watanabe
• Neuroscience Research
• 1999

Diazepam binding inhibitor (DBI), a putative endogenous polypeptide ligand for benzodiazepine (BZD) receptors, has been shown to act as an inverse BZD receptor agonist in the brain. We previously… (More)

The effects of oral melatonin on the autonomic function in healthy subjects.

• Tomoko Kitajima, Takashi Kanbayashi, +6 authors T Shimisu
• Psychiatry and clinical neurosciences
• 2001

We investigated the influence of melatonin on the human autonomic functions by measuring muscle sympathetic nerve activity (MSNA). Five healthy male volunteers took 3 mg of melatonin, and their… (More)

Physiolog,. :oth edition. London: OUP. ERGOTAMINE TARTRATE IN THE TREATMENT OF NARCOLEPSY

• Yoshihiko Kaneko, Hisashi Kumashiro, Keiko Maruko
• 2006

Amphetamine and its related compounds have long been used in the drug therapy of narcolepsy. However, although they have proved effective in treating sleep attacks they have not been so effective in… (More)

Porosity Effect in the Core Thermal Hydraulics for Ultra High Temperature Gas-cooled Reactor

• Motoo FUMIZAWA, Yoshihiko Kaneko
• 2013

This study presents an experimental method of porosity evaluation and a predictive thermal-hydraulic analysis with packed spheres in a nuclear reactor core. The porosity experiments were carried out… (More)

Effect of trazodone in a single dose before bedtime for sleep disorders accompanied by a depressive state: dose-finding study with no concomitant use of hypnotic agent.

• Hirobumi Mashiko, Shin-ichi Niwa, +5 authors Yasuo Watanabe
• Psychiatry and clinical neurosciences
• 1999

This was the first dose-finding study of trazodone that was designed to be free of the concomitant use of hypnotics, in which the drug was administered in a single dose for sleep disorders combined… (More)

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